Efficacy and Safety of Lesinurad in Patients with Hyperuricemia Associated with Gout: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Author: ChangYa-Ting, ChangYu-Sheng, LeeChia-Hwa, LinYing-Chin, LohEl-Wui, TamKa-Wai, WuJie-Ying, WuMei-Yi

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To evaluate the efficacy and safety of lesinurad for the treatment of hyperuricemia in patients with gout. DESIGN: Systematic review and meta-analysis of randomized controlled trials (RCTs). PATIENTS OR PARTICIPANTS: Five RCTs, which included 1959 patients, compared the efficacy and saf...See full text at original site
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引用元:
https://doi.org/10.1002/phar.2183

データ提供:米国国立医学図書館(NLM)

Lesinurad for Hyperuricemia in Gout

Gout, a painful inflammatory condition caused by high levels of uric acid in the blood, can significantly impact a person's quality of life. This study investigates the efficacy and safety of lesinurad, a medication that specifically targets uric acid levels, in treating hyperuricemia associated with gout.

Researchers conducted a meta-analysis of randomized controlled trials, evaluating the effectiveness of lesinurad in lowering uric acid levels and managing gout-related symptoms. Their findings suggest that lesinurad, in combination with other gout medications, can effectively reduce uric acid levels and potentially improve gout symptom control. However, the study highlights the need for further research to determine the long-term clinical implications of lesinurad.

A Targeted Approach to Gout Management

The study highlights the potential of lesinurad to provide a targeted approach to gout management, specifically addressing the underlying cause of the condition. This approach could lead to more effective and personalized treatment strategies for individuals with gout.

Managing Gout

Imagine a desert landscape where the harsh environment can trigger painful, inflammatory conditions. Similarly, gout can cause significant pain and discomfort, impacting a person's ability to function. This research explores new approaches to managing gout, offering hope for a future where individuals can live more comfortably and fulfilling lives.

Dr. Camel's Conclusion

This study sheds light on the potential of lesinurad to improve gout management by specifically addressing the underlying cause of the condition. While further research is needed to fully understand its long-term implications, lesinurad offers a promising new avenue for exploring effective and personalized treatment strategies for individuals with gout.

Date :
  1. Date Completed 2019-09-10
  2. Date Revised 2019-09-10
Further Info :

Pubmed ID

30246299

DOI: Digital Object Identifier

10.1002/phar.2183

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Languages

English

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