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Pharmacokinetics of evocalcet in secondary hyperparathyroidism patients receiving hemodialysis: first-in-patient clinical trial in Japan.
Author: AkizawaTadao, FukagawaMasafumi, ShigematsuTakashi, ShimazakiRyutaro
Original Abstract of the Article :
Cinacalcet is a positive allosteric modulator of calcium-sensing receptors in the parathyroid gland and an effective treatment for secondary hyperparathyroidism. However, this agent has considerable side effects and dosage limitations, which impair effective treatment. Therefore, we investigated the...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141109/
データ提供:米国国立医学図書館(NLM)
Evocalcet: A New Oasis in the Desert of Secondary Hyperparathyroidism Treatment
Secondary hyperparathyroidism, a condition often associated with chronic kidney disease, presents a challenging desert landscape for patients and their healthcare providers. This study investigates the pharmacokinetics, pharmacodynamics, and safety of evocalcet, a novel calcimimetic agent, in patients with secondary hyperparathyroidism undergoing hemodialysis. The researchers found that evocalcet exhibited promising safety and tolerability profiles. This new drug holds the potential to offer a fresh oasis in the desert of treatment options, addressing the limitations of existing therapies.
Navigating the Sands of Secondary Hyperparathyroidism: A New Treatment Option
The study found that evocalcet demonstrated promising pharmacokinetic and pharmacodynamic characteristics. This new agent could offer a more effective and tolerable treatment option for patients with secondary hyperparathyroidism. The researchers' findings provide a valuable roadmap for further exploration and development of this new drug, potentially leading to improved outcomes for patients.
Seeking a Brighter Horizon: New Treatments for Secondary Hyperparathyroidism
This research offers hope for patients with secondary hyperparathyroidism, a condition that can significantly impact quality of life. The development of evocalcet represents a potential new oasis in the desert of treatment options, offering a promising path towards improved management of this complex condition. Further studies will be crucial to fully assess the long-term efficacy and safety of evocalcet, ultimately leading to better outcomes for patients.
Dr.Camel's Conclusion
This research presents a promising new oasis in the desert of secondary hyperparathyroidism treatment. Evocalcet, a novel calcimimetic agent, holds the potential to provide a more effective and tolerable therapeutic option for patients undergoing hemodialysis. Further exploration of this agent could lead to a brighter horizon for individuals struggling with this complex condition.
Date :
- Date Completed n.d.
- Date Revised 2022-03-21
Further Info :
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