Paper Details 
Original Abstract of the Article :
Sodium-glucose cotransporter-2 (SGLT2) inhibitors are effective for overweight diabetic patients through the induction of glucosuria. However, SGLT2 inhibitors are not recommended for patients with advanced chronic kidney disease (CKD) because they may aggravate renal function and thus become less e...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147181/

データ提供:米国国立医学図書館(NLM)

Dapagliflozin: A Potential Treatment for Advanced Diabetic Kidney Disease

Navigating the complexities of diabetes is like traversing a vast desert. Patients with advanced kidney disease face additional challenges as their bodies struggle to regulate blood sugar. This article explores the use of dapagliflozin, an SGLT2 inhibitor, as a potential treatment option for diabetic patients with advanced chronic kidney disease (CKD). SGLT2 inhibitors work by promoting the excretion of glucose in urine, ultimately lowering blood sugar levels. However, their use in patients with advanced CKD has been controversial due to concerns about potential worsening of renal function.

Dapagliflozin: A Promising Solution

The study reviewed five cases of patients with advanced CKD who received dapagliflozin treatment. The results were remarkable! The patients showed significant weight reduction, improved blood sugar control, and experienced further benefits without any worsening of their kidney function. This suggests that dapagliflozin might be a safe and effective treatment option for patients with advanced CKD, defying previous concerns.

Hydration: A Crucial Element for Effective Treatment

The researchers emphasize the importance of adequate hydration when administering dapagliflozin to patients with advanced CKD. Just as a desert needs water to flourish, patients with CKD require sufficient fluids to support proper kidney function. This is a crucial factor in preventing any potential side effects of dapagliflozin therapy.

Dr. Camel's Conclusion

This study offers a ray of hope for patients with advanced diabetic kidney disease. The positive results with dapagliflozin suggest a new path forward for managing diabetes in this challenging patient population. It's a reminder that the desert of medical knowledge is constantly evolving, and new solutions are always emerging.

Date :
  1. Date Completed n.d.
  2. Date Revised 2020-10-01
Further Info :

Pubmed ID

30254854

DOI: Digital Object Identifier

PMC6147181

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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