Opicapone for the treatment of Parkinson's disease: A review of a new licensed medicine.

Author: FabbriMargherita, FerreiraJoaquim J, LeesAndrew, PoeweWerner, RascolOlivier, StocchiFabrizio, TolosaEduardo

Paper Details 
Original Abstract of the Article :
Catechol-O-methyl transferase inhibitors are currently used as first-line add-on therapy to levodopa for the treatment of end-of-dose motor fluctuations in Parkinson's disease patients, as they increase levodopa bioavailability. Several factors hamper the use of current available catechol-O-methyl t...See full text at original site
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引用元:
https://doi.org/10.1002/mds.27475

データ提供:米国国立医学図書館(NLM)

Opicapone: A New Hope for Parkinson's Disease?

Parkinson's disease, like a shifting desert landscape, presents numerous challenges for patients and researchers alike. This study, like a camel carrying precious water, explores a new therapeutic approach for managing Parkinson's disease. Opicapone, a long-acting, peripherally selective catechol-O-methyl transferase inhibitor, is a promising new addition to the treatment arsenal for Parkinson's disease. This study analyzes the clinical pharmacological data of opicapone, providing an overview of its efficacy and safety. The authors delve into opicapone's potential role in managing motor fluctuations, a common and debilitating symptom of Parkinson's disease.

A Beacon of Hope for Managing Motor Fluctuations

Opicapone, like a beacon in the desert, has demonstrated efficacy in reducing OFF time, a crucial metric in Parkinson's disease management. The study shows that opicapone can reduce OFF time by an average of 60 minutes daily, without increasing ON time with troublesome dyskinesias. These findings offer a potential improvement in the quality of life for Parkinson's patients, providing them with longer periods of mobility and independence.

Navigating the Challenges of Parkinson's Disease

Opicapone, like a cool breeze in the desert, has shown a good safety profile. This is encouraging news for patients who are seeking a safe and effective treatment option. It's a reminder that research continues to offer new hope for improving the lives of those living with Parkinson's disease. As we continue to explore the shifting sands of this complex condition, it's essential to remember that even small steps forward can make a significant difference.

Dr.Camel's Conclusion

This study, like a refreshing oasis in the desert, provides a glimmer of hope for Parkinson's disease patients. It showcases the potential of opicapone as a valuable therapeutic tool for managing motor fluctuations, offering the promise of increased mobility and a better quality of life for individuals living with this challenging condition.

Date :
  1. Date Completed 2019-10-15
  2. Date Revised 2019-10-15
Further Info :

Pubmed ID

30264443

DOI: Digital Object Identifier

10.1002/mds.27475

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Languages

English

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