Paper Details 
Original Abstract of the Article :
Preclinical studies indicate that lorcaserin (Belviq®), an FDA-approved serotonin 2 C receptor agonist, may be a promising medication for the treatment of stimulant addiction. However, few studies have investigated its effects on self-administration of drugs of abuse from other pharmacological class...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/30268662

データ提供:米国国立医学図書館(NLM)

Lorcaserin: A Potential Treatment for Opioid Addiction?

The world of drug addiction research is a vast and complex desert, filled with challenges and mysteries. One particularly challenging area is the search for effective treatments for opioid addiction. This research, published in the journal Neuropsychopharmacology, delves into the potential of lorcaserin, an FDA-approved medication for weight loss, as a treatment for opioid addiction. The study used rhesus monkeys as a model for human addiction, a common practice in this field as these monkeys are highly susceptible to opioid addiction. This study investigated the effects of lorcaserin on both heroin and food self-administration in these monkeys. The researchers discovered that lorcaserin selectively decreased heroin intake without impacting food intake, suggesting a possible avenue for treating opioid addiction without causing unwanted effects on food intake. This finding is quite fascinating and promising, as it suggests a potential new treatment for opioid addiction that might not impact food intake. This research has implications for the development of new treatments for opioid addiction.

Lorcaserin: A Targeted Approach to Opioid Addiction

The research showed that lorcaserin decreased heroin intake by selectively reducing its reinforcing strength. This finding suggests that lorcaserin might help to break the cycle of addiction by reducing the pleasurable effects of opioids without impacting the desire for food. It's like trying to quench a thirst in a desert with a specific water source, rather than just any water source. This targeted approach could be key in helping individuals break free from the hold of addiction and regain control over their lives.

Lorcaserin: A New Hope for Opioid Addiction Treatment?

The findings of this study suggest that lorcaserin may be a promising new treatment option for opioid addiction. The selective nature of lorcaserin's effects on opioid self-administration is particularly encouraging. By reducing the rewarding effects of opioids without affecting food intake, lorcaserin could potentially provide a safer and more effective treatment option for individuals struggling with opioid addiction. This research is a glimmer of hope in the vast, sometimes seemingly endless desert of opioid addiction. We need to continue to investigate this promising avenue and explore its potential for treating opioid addiction in humans.

Dr. Camel's Conclusion

This study on lorcaserin is a promising development in the search for new opioid addiction treatments. Its selective impact on opioid self-administration, without affecting food intake, suggests a potentially safer and more effective approach for individuals battling addiction. While further research is needed, the findings offer a glimmer of hope in the vast, challenging desert of opioid addiction.

Date :
  1. Date Completed 2019-01-22
  2. Date Revised 2019-12-10
Further Info :

Pubmed ID

30268662

DOI: Digital Object Identifier

NIHMS1509831

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Languages

English

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