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Pulmonary adverse events related to idelalisib therapy: A single centre experience.
Author: Bani-SadrFirouzé, DelmerAlain, GiltatAurélien, JulienGautier, LebargyFrançois, LebrunDelphine, MigaultCaroline, NguyenYohan, ToubasDominique, ToubasOlivier
Original Abstract of the Article :
Idelalisib is a potent and selective inhibitor of the PI3Kδ approved since September 2014 for the treatment of several types of B cell malignancies. Pulmonary adverse events related to idelalisib are an emerging serious adverse event. We report here a single centre cohort of 16 patients who initiate...See full text at original site
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引用元:
https://doi.org/10.1080/1120009X.2018.1516184
データ提供:米国国立医学図書館(NLM)
Idelalisib: A Powerful Drug with Potential Pulmonary Side Effects
In the fight against [B cell malignancies], we have a new weapon: [idelalisib]. This drug, a potent inhibitor of [PI3Kδ], shows promise in treating various B cell cancers. However, like a powerful oasis in a vast desert, it comes with potential dangers, including [pulmonary adverse events]. This research explores the occurrence of [pulmonary adverse events] in patients receiving idelalisib.
This research, based on a single-center cohort of 16 patients, found that 5 patients experienced severe pulmonary adverse events. These events included [infectious pneumonia] and/or [drug-induced pneumonitis], which are potentially serious complications.
Navigating the Desert of Side Effects
This research emphasizes the importance of being aware of the potential side effects of powerful drugs. While idelalisib offers hope for patients with B cell malignancies, it’s crucial to be vigilant for any signs of pulmonary problems and to seek prompt medical attention if they occur.
Taking Precautions with Powerful Drugs
This study highlights the potential for severe pulmonary adverse events related to idelalisib therapy. It emphasizes the importance of careful monitoring for any signs of respiratory distress in patients receiving this drug, a crucial step in navigating the potential dangers that come with powerful medications, much like a camel navigating a challenging desert landscape.
Dr. Camel's Conclusion
This study underscores the importance of being aware of the potential side effects of powerful drugs like idelalisib. While this drug offers hope for patients with B cell malignancies, it is essential to monitor patients closely for any signs of pulmonary complications, allowing us to effectively manage these potential risks and maximize the benefits of this important therapy.
Date :
- Date Completed 2019-06-18
- Date Revised 2021-12-04
Further Info :
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