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Emerging pharmacotherapeutic approaches for the management of sickle cell disease.

Author: ConranNicola, TorresLidiane

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Several new pharmacotherapies for sickle cell disease (SCD) are in late-stage development, targeting specific pathophysiological mechanisms. These include voxelotor, prasugrel, and crizanlizumab, which show promise in preventing vaso-occlusive episodes.
Paper Details　
Original Abstract of the Article :
INTRODUCTION: Sickle cell disease (SCD) is an inherited disease with lifelong morbidity, whose complications include frequent acute painful vaso-occlusive episodes (VOEs) that often require hospitalization. The only pharmacotherapy currently in regular use for SCD management is hydroxyurea (hydroxyc...See full text at original site
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引用元：
https://doi.org/10.1080/14656566.2018.1548610

データ提供：米国国立医学図書館（NLM）

New Hope in the Desert: Emerging Therapies for Sickle Cell Disease

Sickle cell disease (SCD) is a genetic disorder that can cause chronic pain and other complications. It's like living in a harsh desert environment, where the body's red blood cells are misshapen and struggle to carry oxygen. This study explores new drug therapies that are being developed to manage SCD.

Oasis of Hope: Emerging Therapies for Sickle Cell Disease

Researchers are working to develop new drugs that target the specific mechanisms of SCD, like finding oases of relief in the desert. They're exploring both preventative and abortive therapies that can reduce the frequency and severity of painful episodes. These drugs are like finding new routes and resources to navigate the challenges of SCD.

A Journey to Better Health: Managing Sickle Cell Disease

The development of new therapies is a beacon of hope for people living with SCD. These treatments offer the promise of a more comfortable and fulfilling life, like finding a well-stocked caravan ready to journey through the desert.

Dr. Camel's Conclusion

New therapies are emerging in the desert landscape of SCD, offering hope for a brighter future. These treatments are like finding new oases and resources to manage the challenges of this genetic disorder, paving the way for better health and quality of life.

Date :
  1. Date Completed 2019-01-28
  2. Date Revised 2019-12-10
Further Info :

Pubmed ID

30499731

DOI: Digital Object Identifier

10.1080/14656566.2018.1548610

Related Literature

Article Analysis
・Effects of voxelotor
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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