Isavuconazole and voriconazole for the treatment of chronic pulmonary aspergillosis: A retrospective comparison of rates of adverse events.

Author: BongominFelix, FeltonTimothy, MaguireNiamh, MooreCaroline B, Rautemaa-RichardsonRiina

Paper Details 
Original Abstract of the Article :
Long-term oral triazole antifungal therapy is the cornerstone of management for patients with chronic pulmonary aspergillosis (CPA). Itraconazole is the first-line choice of treatment. Voriconazole, posaconazole or isavuconazole can be used as alternative treatments in case of resistance or intolera...See full text at original site
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引用元:
https://doi.org/10.1111/myc.12885

データ提供:米国国立医学図書館(NLM)

Navigating the Tricky Terrain of Chronic Pulmonary Aspergillosis

Chronic pulmonary aspergillosis (CPA) is a serious lung infection, like a persistent sandstorm in the respiratory system. Treating CPA involves long-term antifungal medications, but these drugs can cause side effects, similar to a desert traveler facing the harsh elements. This study compares the side effects of three common antifungal medications: isavuconazole, voriconazole, and itraconazole. Itraconazole is often the first-line treatment, but if it doesn’t work or causes problems, the other two are options. The researchers reviewed medical records of patients with CPA and found that all three drugs had similar rates of side effects.

Side Effects: A Constant in the Desert

This study suggests that all three antifungal medications, isavuconazole, voriconazole, and itraconazole, have a similar risk of side effects. This underscores the need for careful monitoring and management of potential complications when treating CPA.

Finding the Right Oasis: Managing Side Effects in CPA

This study highlights the ongoing challenge of balancing the benefits and risks of antifungal medications in treating CPA. Just as a desert traveler needs to find the right oasis to rest and replenish, patients with CPA need to work closely with their doctors to manage side effects and find the most effective treatment strategies.

Dr. Camel's Conclusion

This study, like a caravan of medical professionals navigating the desert of CPA, highlights the complexities of managing side effects associated with antifungal treatments. While these medications offer valuable hope for managing this serious infection, it’s crucial to remain vigilant in monitoring potential complications and ensuring patients find the right oasis of care to help them through their journey.

Date :
  1. Date Completed 2019-03-18
  2. Date Revised 2019-03-18
Further Info :

Pubmed ID

30570179

DOI: Digital Object Identifier

10.1111/myc.12885

Related Literature

SNS
PICO Info
in preparation
Languages

English

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