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Statin therapy in the treatment of active cancer: A systematic review and meta-analysis of randomized controlled trials.

Author: Dhesy-ThindSukhbinder K, EllisPeter, FarooqiMohammed A M, LeongDarryl P, MalhotraNikita, MukherjeeSom D, SangerStephanie

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Statins have shown anti-tumor properties in preclinical studies and observational studies suggest that cancer patients on statins may have improved survival and cancer-specific outcomes. This study aimed to evaluate the randomized controlled trials of statins in addition to standard anti-cancer therapy.
Paper Details　
Original Abstract of the Article :
Preclinical evidence suggests statins may have anti-tumor properties. Large observational studies are also consistent with improved survival and cancer-specific outcomes among cancer patients on statins. We sought to evaluate the randomized controlled trials of statins in addition to usual anti-canc...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301687/

データ提供：米国国立医学図書館（NLM）

Statins: A Potential Ally in the Fight Against Cancer?

This research examines the role of statins, commonly used to lower cholesterol, in the treatment of active cancer. The study reviews the preclinical evidence suggesting that statins may have anti-tumor properties and examines the results of randomized controlled trials investigating the use of statins in conjunction with standard cancer therapies.

Statins: A Promising Adjunct Therapy for Cancer

The study found that while observational studies suggest a potential association between statin use and improved cancer outcomes, the results of randomized controlled trials are less conclusive. While some studies show a potential benefit of statins, the evidence is not yet strong enough to recommend statins as a standard treatment for cancer.

Statins: Further Research is Needed

The study highlights the need for further research to fully understand the potential benefits and risks of statin therapy in cancer patients. Just as a camel needs to carefully assess its resources before embarking on a long desert journey, researchers need to conduct more rigorous studies to guide the use of statins in cancer treatment.

Dr.Camel's Conclusion

This research emphasizes the need for ongoing research to explore the complex relationship between statins and cancer. Like a camel navigating a changing desert landscape, scientists must adapt their approaches and remain open to new discoveries.

Date :
  1. Date Completed 2019-05-27
  2. Date Revised 2020-03-09
Further Info :

Pubmed ID

30571754

DOI: Digital Object Identifier

PMC6301687

Related Literature

Article Analysis
・Effective treatment of statins
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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