Real-life results of treatment with ombitasvir, paritaprevir, dasabuvir, and ritonavir combination in patients with chronic renal failure infected with HCV in Turkey.

Author: AltıntaşEngin, AteşFehmi, SezginOrhan, YaraşSerkan, ÖzdoğanOsman, ÜçbilekEnver

Paper Details 
Original Abstract of the Article :
As the most common liver disease in hemodialysis patients, chronic hepatitis C (CHC) can cause cirrhosis and hepatocellular carcinoma, even increase in renal-related mortality. In Turkey, the frequency of anti-hepatitis C virus (HCV) antibodies in hemodialysis patients ranged from 31.4% to 51%. Unti...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453652/

データ提供:米国国立医学図書館(NLM)

Treating Hepatitis C in Patients with Chronic Renal Failure

Chronic hepatitis C (CHC) is a major concern for patients with chronic renal failure (CRF), especially those undergoing hemodialysis. This study examines the effectiveness of a novel drug combination, known as the 3D regimen, in treating CHC in patients with CRF. This 3D regimen consists of four drugs: ombitasvir, paritaprevir, dasabuvir, and ritonavir, and it is a promising alternative to the older, more toxic treatments.

The study focused on patients in Turkey who were infected with genotype 1a and 1b HCV and were undergoing hemodialysis. The researchers meticulously tracked the outcomes of treatment with the 3D regimen, finding that it showed promising results in these patients. The results suggest that this combination therapy may offer a safe and effective way to treat CHC in a population that is often challenging to manage due to their underlying kidney issues.

A New Hope for Chronic Hepatitis C Treatment

The findings of this study are encouraging for patients with CHC and CRF. This new 3D regimen offers a potentially safer and more effective treatment option, potentially improving the lives of many patients. The results show a significant improvement in the treatment of CHC in hemodialysis patients, offering hope for a better future.

Hope for a Healthier Future

This research reinforces the importance of developing new and effective therapies for patients with complex medical conditions, like chronic hepatitis C and chronic renal failure. It demonstrates the progress made in medical research and the dedication of scientists to finding solutions for those in need.

Dr. Camel's Conclusion

This study, like a cool oasis in the scorching heat of a disease, offers a refreshing solution to the challenges of treating hepatitis C in patients with chronic kidney failure. By combining knowledge and innovation, we can create a more hopeful future for patients with chronic health conditions.

Date :
  1. Date Completed 2019-12-24
  2. Date Revised 2021-12-04
Further Info :

Pubmed ID

30666967

DOI: Digital Object Identifier

PMC6453652

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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