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Adaptogens in chemobrain (Part I): Plant extracts attenuate cancer chemotherapy-induced cognitive impairment - Transcriptome-wide microarray profiles of neuroglia cells.

Author: EfferthThomas, KlauckSabine M, PanossianAlexander, SeoEan-Jeong

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Cancer chemotherapy can cause cognitive impairment, possibly due to its effects on brain cells. Adaptogens, natural substances known to enhance stress resilience, have shown neuroprotective effects and improved cognitive function in clinical studies.
Paper Details　
Original Abstract of the Article :
Cancer chemotherapy-induced cognitive impairments are presumably associated with undesirable effects of chemotherapy on physiological functions of brain cells. Adaptogens are natural compounds or plant extracts increasing an organism's adaptability and survival in stress. They exhibited neuroprotect...See full text at original site
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引用元：
https://doi.org/10.1016/j.phymed.2018.10.022

データ提供：米国国立医学図書館（NLM）

Chemobrain: A Foggy Desert

Cancer chemotherapy, a powerful weapon against cancer, can sometimes leave patients feeling like they're navigating a foggy desert. This condition, known as chemobrain, involves cognitive impairments that can significantly affect quality of life. This research explores the potential of adaptogens, natural compounds known to enhance resilience, in combating chemobrain.

Adaptogens: A Potential Oasis in the Fog

The study focused on the effects of adaptogens on brain cells, specifically neuroglia cells, which support and protect neurons. Researchers examined transcriptome-wide microarray profiles of neuroglia cells, revealing that adaptogens can potentially attenuate the detrimental effects of chemotherapy on brain cell function. The results suggest that adaptogens could offer a promising avenue for mitigating chemobrain and improving cognitive function in cancer patients undergoing chemotherapy.

Navigating the Fog with Adaptogens

This research offers a glimmer of hope in the desert of chemobrain. Adaptogens, with their potential neuroprotective effects, could provide a natural approach to improving cognitive function and reducing the cognitive fog experienced by cancer patients. Further research is needed to explore the potential of adaptogens in this context, but the findings provide a promising starting point for developing new strategies to combat chemobrain and improve the lives of cancer patients.

Dr. Camel's Conclusion

This research is like a flickering lantern illuminating a potential path through the fog of chemobrain. Adaptogens, with their potential to enhance resilience and protect brain cells, could offer a natural and promising approach to managing cognitive impairment. Just as a traveler in the desert relies on a reliable source of water, cancer patients struggling with chemobrain might find solace in the potential of adaptogens to enhance their cognitive well-being.
Date :
  1. Date Completed 2019-06-24
  2. Date Revised 2019-06-24
Further Info :

Pubmed ID

30668446

DOI: Digital Object Identifier

10.1016/j.phymed.2018.10.022

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English

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