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Choosing appropriate pharmacotherapy for drug-resistant HIV.

Author: CapettiAmedeo, RizzardiniGiuliano

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Despite the effectiveness of antiretroviral therapy, some patients develop drug resistance due to factors such as non-adherence, limited drug availability, and economic constraints. Drug resistance can lead to treatment failure and further complicate HIV management. This review explores the literature on drug resistance, its causes, and potential strategies to mitigate the impact of resistance.
Paper Details　
Original Abstract of the Article :
Despite the potency of current antiretrovirals, some patients continue to struggle with the management of the treatment of HIV due to drug resistance-associated mutations. The underlying causes of these developments are usually drug adherence and drug availability as well as the economic affordabili...See full text at original site
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引用元：
https://doi.org/10.1080/14656566.2019.1570131

データ提供：米国国立医学図書館（NLM）

Navigating Drug-Resistant HIV: Choosing Appropriate Pharmacotherapy

The development of drug resistance poses a significant challenge in the management of HIV infection. This review explores the factors contributing to drug resistance and the strategies for choosing appropriate pharmacotherapy in these challenging cases.

Addressing Drug Resistance: A Multifaceted Approach

Researchers emphasize the importance of addressing drug resistance, highlighting the role of patient adherence, drug availability, and economic affordability in influencing treatment outcomes. They highlight the need for a strategic vision when choosing new regimens, considering factors such as genetic barrier, convenience, potency, drug-drug interactions, and tolerability.

A Desert of Drug Resistance: Finding New Paths

Think of drug resistance as a vast desert, where HIV can thrive and evade conventional treatments. Finding new paths through this desert requires a multifaceted approach, including preventive interventions, the development of new compounds, and strategies to minimize the emergence and transmission of drug-resistant mutations.

Dr. Camel's Conclusion

This review underscores the complexities of drug resistance in HIV treatment, highlighting the need for continued research and innovation to develop effective strategies for managing this challenging aspect of HIV care. The authors emphasize the importance of preventive interventions, patient education, and access to appropriate medications to optimize treatment outcomes.

Date :
  1. Date Completed 2019-04-08
  2. Date Revised 2019-04-08
Further Info :

Pubmed ID

30676115

DOI: Digital Object Identifier

10.1080/14656566.2019.1570131

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Languages

English

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