Long term treatment with stimulant laxatives - clinical evidence for effectiveness and safety?

Author: Bring ChristensenMikkel, Jimenez-SolemEspen, NoergaardMia, Traerup AndersenJon

Paper Details 
Original Abstract of the Article :
Bisacodyl and sodium picosulfate are classified both as stimulant laxatives, approved for short-term treatment of constipation and sold without prescription (OTC). Stimulant laxatives are associated with harmful long-term colonic effects and possible carcinogenic risk - and evidence support that the...See full text at original site
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引用元:
https://doi.org/10.1080/00365521.2018.1563806

データ提供:米国国立医学図書館(NLM)

Stimulant Laxatives: A Long-Term Perspective in the Desert of Constipation

The study examines the effectiveness and safety of [stimulant laxatives] for long-term treatment of [constipation]. The authors conducted a comprehensive review of clinical trial evidence, highlighting the potential risks and benefits associated with the long-term use of these medications. They found limited evidence to support the efficacy and safety of stimulant laxatives for prolonged treatment, raising concerns about their potential for adverse effects on the colon.

Stimulant Laxatives: A Double-Edged Sword in the Desert of Constipation

This study sheds light on the potential risks associated with the long-term use of stimulant laxatives for constipation. The authors warn that these medications may not be suitable for prolonged treatment, highlighting the importance of carefully considering their potential for adverse effects. This finding is comparable to discovering a double-edged sword in the desert, where its potential benefits must be weighed against its potential dangers.

Navigating the Desert of Constipation with Caution

The study emphasizes the need for a cautious approach to the long-term use of stimulant laxatives. The authors recommend exploring alternative treatment options and carefully monitoring patients for potential adverse effects. This is akin to navigating a desert, where a thorough understanding of the terrain and potential hazards is crucial for a safe and successful journey. By carefully considering the risks and benefits of different treatment options, clinicians can provide optimal care and minimize the risk of complications for patients with constipation.

Dr.Camel's Conclusion

This study underscores the need for caution in the long-term use of stimulant laxatives, highlighting the limited evidence supporting their efficacy and safety in this context. The researchers recommend exploring alternative treatment options and carefully monitoring patients for potential adverse effects, ensuring a safe and effective approach to managing constipation.

Date :
  1. Date Completed 2019-05-13
  2. Date Revised 2019-05-13
Further Info :

Pubmed ID

30700194

DOI: Digital Object Identifier

10.1080/00365521.2018.1563806

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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