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Long term treatment with stimulant laxatives - clinical evidence for effectiveness and safety?
Author: Bring ChristensenMikkel, Jimenez-SolemEspen, NoergaardMia, Traerup AndersenJon
Original Abstract of the Article :
Bisacodyl and sodium picosulfate are classified both as stimulant laxatives, approved for short-term treatment of constipation and sold without prescription (OTC). Stimulant laxatives are associated with harmful long-term colonic effects and possible carcinogenic risk - and evidence support that the...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1080/00365521.2018.1563806
データ提供:米国国立医学図書館(NLM)
Stimulant Laxatives: A Long-Term Perspective in the Desert of Constipation
The study examines the effectiveness and safety of [stimulant laxatives] for long-term treatment of [constipation]. The authors conducted a comprehensive review of clinical trial evidence, highlighting the potential risks and benefits associated with the long-term use of these medications. They found limited evidence to support the efficacy and safety of stimulant laxatives for prolonged treatment, raising concerns about their potential for adverse effects on the colon.
Stimulant Laxatives: A Double-Edged Sword in the Desert of Constipation
This study sheds light on the potential risks associated with the long-term use of stimulant laxatives for constipation. The authors warn that these medications may not be suitable for prolonged treatment, highlighting the importance of carefully considering their potential for adverse effects. This finding is comparable to discovering a double-edged sword in the desert, where its potential benefits must be weighed against its potential dangers.
Navigating the Desert of Constipation with Caution
The study emphasizes the need for a cautious approach to the long-term use of stimulant laxatives. The authors recommend exploring alternative treatment options and carefully monitoring patients for potential adverse effects. This is akin to navigating a desert, where a thorough understanding of the terrain and potential hazards is crucial for a safe and successful journey. By carefully considering the risks and benefits of different treatment options, clinicians can provide optimal care and minimize the risk of complications for patients with constipation.
Dr.Camel's Conclusion
This study underscores the need for caution in the long-term use of stimulant laxatives, highlighting the limited evidence supporting their efficacy and safety in this context. The researchers recommend exploring alternative treatment options and carefully monitoring patients for potential adverse effects, ensuring a safe and effective approach to managing constipation.
Date :
- Date Completed 2019-05-13
- Date Revised 2019-05-13
Further Info :
Related Literature
English
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