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Which antimuscarinic agents used in the treatment of overactive bladder increase heart rate? a prospective randomized clinical trial.
Author: CetinelBulent, DincerMurat, GultekinMehmet Hamza, GuzelsoyMuhammed, OnalBulent, TuregunFethi Ahmet
Original Abstract of the Article :
PURPOSE: To compare the heart rate increase side effect of different antimuscarinic drugs used in overactive bladder (OAB). METHODS: Overall 341 patients were consecutively randomized to take seven different antimuscarinic drugs between January 2014 and June 2016 at three institutions, and 250 pati...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1007/s11255-019-02090-9
データ提供:米国国立医学図書館(NLM)
Which Antimuscarinic Agents Increase Heart Rate?
We're all about keeping things moving smoothly, right? That's why this study is a real camel-back breaker! It dives into the world of antimuscarinic drugs, those trusty companions in managing an overactive bladder. Like a caravan navigating a sandy desert, these drugs help control the flow of things, but some can have unexpected side effects. This study used a randomized clinical trial to compare the heart rate increase side effect of different antimuscarinic drugs.
The researchers discovered that non-selective antimuscarinic drugs, like a camel trying to carry too much cargo, were more likely to lead to an increased heart rate. Specifically, trospium chloride, tolterodine tartrate, fesoterodine fumarate, and propiverine hydrochloride were the real culprits. This is like a camel trying to cross a shifting sand dune – you need to be careful to avoid a tumble!
Non-Selective Antimuscarinic Drugs Increase Heart Rate
The study showed a statistically significant increase in heart rate for patients taking non-selective antimuscarinic drugs. This means that there's a good chance that these drugs will increase your heart rate, especially if you're using trospium chloride, tolterodine tartrate, fesoterodine fumarate, or propiverine hydrochloride.
Heart Rate and Your Health
A faster heart rate can be a sign of an overactive bladder. It's important to talk to your doctor about the potential side effects of any medication you're taking. If you're experiencing an increased heart rate, especially if it's accompanied by other symptoms like chest pain or shortness of breath, it's important to seek medical attention. You wouldn't want to be stuck in the middle of the desert without a well-stocked camel!
Dr. Camel's Conclusion
This study provides valuable insight into the potential side effects of different antimuscarinic medications. Like a well-trained camel, we must be aware of the potential risks and benefits of any treatment we choose. Consult with your doctor to find the best solution for your specific needs and ensure a smooth journey through your health!
Date :
- Date Completed 2019-08-12
- Date Revised 2020-02-25
Further Info :
Related Literature
English
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