The dilemma of metastatic medullary thyroid carcinoma: when to start systemic treatment.

Author: AlfieriSalvatore, BergaminiCristiana, CalaresoGiuseppina, GranataRoberta, LocatiLaura Deborah, OrlandiEster, SianoMarco

Paper Details 
Original Abstract of the Article :
Label="PURPOSE" NlmCategory="OBJECTIVE">Two tyrosine kinase inhibitors (TKIs), vandetanib and cabozantinib, have been approved for recurrent/metastatic (R/M) medullary thyroid carcinoma (MTC). To date, it is still debated when and which TKI has to be started in R/M MTC patients. This is due to 1) TK...See full text at original site
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引用元:
https://doi.org/10.1177/0300891619829571

データ提供:米国国立医学図書館(NLM)

The Evolving Landscape of Medullary Thyroid Carcinoma Treatment

This case study highlights the [challenges] in treating [metastatic medullary thyroid carcinoma (MTC)]. The availability of [tyrosine kinase inhibitors (TKIs)] has ushered in a new era of treatment, but determining [when and which TKI] to use remains a complex question. This study sheds light on the [unique challenges] presented by MTC, particularly the [discordant disease behavior] observed in this case, where some tumors regressed spontaneously while others progressed.

Navigating the Sand Dunes of Treatment Decisions

The authors raise important questions about the [optimal timing for starting TKIs] in MTC patients. These questions are akin to navigating a shifting sand dune landscape - the terrain is constantly changing, and the best path forward is not always clear. The study highlights the need for [individualized treatment plans] that consider the [specific characteristics] of each patient's disease.

A New Oasis of Treatment Options

This case study emphasizes the evolving nature of [MTC treatment]. With new therapies emerging, it is essential to stay abreast of the latest advancements and adapt treatment strategies accordingly. This is like discovering a new oasis in the desert – it requires careful exploration and a willingness to embrace new knowledge.

Dr.Camel's Conclusion

This study serves as a reminder that [treating MTC] requires a nuanced approach that considers the [individual characteristics] of each patient. It is a testament to the ever-changing landscape of cancer treatment, where new therapies are constantly emerging, but careful consideration and personalized strategies are crucial for navigating the desert of disease.

Date :
  1. Date Completed 2020-01-22
  2. Date Revised 2022-04-12
Further Info :

Pubmed ID

30782103

DOI: Digital Object Identifier

10.1177/0300891619829571

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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