Optogenetic control of the enteric nervous system and gastrointestinal transit.

Author: FengJing, HibberdTim, HuHongzhen, SpencerNick J

Paper Details 
Original Abstract of the Article :
There are limited effective therapies available for improving gastrointestinal (GI) transit in mammals with intractable or chronic constipation. Current therapeutics to improve GI-transit usually require oral ingestion of therapeutic drugs, such as the serotonin receptor agonist prucalopride. Howeve...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/30791770

データ提供:米国国立医学図書館(NLM)

Optogenetics: A Light-Based Approach to Gastrointestinal Health

This research explores the exciting world of optogenetics, a cutting-edge technique that uses light to control specific cells within the body. This innovative approach has the potential to revolutionize the treatment of gastrointestinal disorders, particularly constipation. It's like discovering a new way to control the flow of water in the desert, directing it to the areas that need it most. The study focuses on using optogenetics to selectively stimulate the enteric nervous system (ENS), the brain of the gut, to improve gastrointestinal transit.

Optogenetics Offers a Targeted Approach to Gut Health

This study reveals the potential of optogenetics to precisely target the ENS, effectively addressing constipation without affecting other organs. This is like finding a way to create a new channel for the flow of water, ensuring it reaches the desired destination without spilling over into other areas of the desert.

A New Horizon for Treating Constipation

This research offers a promising new avenue for treating constipation. It's like discovering a new oasis with a powerful and precise system for managing the flow of water, offering a potential solution for those struggling with this common issue.

Dr.Camel's Conclusion

Optogenetics has the potential to transform our understanding of gastrointestinal health. This groundbreaking approach offers a new way to address challenging issues like constipation, potentially leading to more effective and targeted treatments. Imagine a future where we can manage the flow of water in the desert with precision and control, guiding it to where it's needed most. Optogenetics opens a new chapter in this journey, offering exciting possibilities for improving the lives of those facing gastrointestinal challenges.
Date :
  1. Date Completed 2019-06-25
  2. Date Revised 2020-05-14
Further Info :

Pubmed ID

30791770

DOI: Digital Object Identifier

NIHMS1048296

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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