Efficacy of saliva substitutes and stimulants in the treatment of dry mouth.

Author: EncisoReyes, HanPhuu P, MohammadiMehdi, MulliganRoseann, SeeLydia

Paper Details 
Original Abstract of the Article :
AIMS: To evaluate the efficacy of saliva substitutes and stimulants compared to placebo in improving findings of dry mouth not caused by Sjӧgren's. METHODS AND RESULTS: Four databases were searched (PubMed, Web of Science, Cochrane Library, and EMBASE) through March 2018. Only randomized controlled...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1111/scd.12370

データ提供:米国国立医学図書館(NLM)

Exploring the Oasis of Saliva Substitutes and Stimulants

In the vast desert of dry mouth, we are always seeking solutions to quench our parched throats. This study delves into the realm of saliva substitutes and stimulants, examining their effectiveness in treating dry mouth, a condition that often feels like a relentless sandstorm in our mouths. The researchers, like intrepid explorers, embarked on a quest through a sea of scientific literature, sifting through 348 studies, ultimately focusing on seven randomized controlled trials (RCTs) involving 257 dry mouth patients. Their objective was to compare the effectiveness of these treatments to a placebo, the control group, in a bid to determine if these solutions can truly create a calming oasis in the desert of dry mouth.

1% Malic Acid Emerges as a Potential Oasis

The results of their exploration suggest that 1% malic acid topical spray emerges as a potential oasis in the desert of dry mouth. In two studies, the researchers found that 1% malic acid significantly increased both unstimulated and stimulated salivary flow compared to the placebo, akin to a refreshing spring welling up in the middle of a barren wasteland. This positive effect extended to patient-reported improvement, with patients using 1% malic acid topical spray being 5.4 times more likely to experience improvement compared to the placebo group. It's like finding a hidden oasis with shimmering waters, offering respite from the aridity.

Hydrating Our Mouths, A Vital Oasis in Our Well-Being

This research offers hope to individuals battling dry mouth. It highlights the potential of 1% malic acid topical spray to provide relief and improve quality of life for those struggling with the discomfort of dry mouth. The findings suggest that exploring natural solutions like 1% malic acid may hold the key to creating a more comfortable and hydrated experience. However, it is important to remember that the quality of the evidence was low, a reminder that further research is needed to solidify the findings and provide a comprehensive oasis of knowledge for those seeking relief.

Dr. Camel's Conclusion

This research, like an oasis in the desert, offers a glimmer of hope for those seeking relief from dry mouth. While 1% malic acid topical spray shows promise, further research is crucial to validate its effectiveness and ensure its long-term benefit. We must continue our explorations in this vast desert of medical knowledge to find lasting solutions for our patients, like discovering a hidden oasis that can quench thirst and provide lasting solace.

Date :
  1. Date Completed 2019-11-26
  2. Date Revised 2022-05-31
Further Info :

Pubmed ID

30811076

DOI: Digital Object Identifier

10.1111/scd.12370

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.