Retrospective Analysis of Skin Toxicity in Patients under Anti-EGFR Tyrosine Kinase Inhibitors: Our Experience in Lung Cancer.

Author: AnnunziataMaria Carmela, CinelliEleonora, FabbrociniGabriella, FerrilloMaria, PanarielloLuigia, RoccoDanilo

Paper Details 
Original Abstract of the Article :
Tyrosine kinase inhibitors (TKIs) have been introduced for the treatment of lung cancer, improving progression-free survival, objective response rate, and quality of life. However, TKIs can lead to cutaneous toxicities, including papulopustular rash, xerosis, paronychia with/without pyogenic granulo...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454160/

データ提供:米国国立医学図書館(NLM)

Skin Toxicity Associated with Anti-EGFR Tyrosine Kinase Inhibitors in Lung Cancer

The vast desert of cancer research continues to yield new weapons against this formidable foe. Tyrosine kinase inhibitors (TKIs) are a class of drugs that have revolutionized the treatment of lung cancer, offering hope to many patients. However, like a mirage in the desert, TKIs can also have side effects, including skin toxicity.

This study examines the incidence and types of skin toxicity observed in patients with lung cancer who were treated with TKIs. The researchers reviewed data from a cohort of lung cancer patients and identified various forms of skin toxicity, such as papulopustular rash, xerosis, paronychia, and scalp disorders. They also observed facial hair and/or eyelash growth.

The Importance of Monitoring Skin Toxicity in TKI Therapy

The study highlights the importance of monitoring skin toxicity in patients receiving TKI therapy. This knowledge can help clinicians manage these side effects and improve patients' quality of life. This is like recognizing the warning signs of a looming sandstorm in the desert so that we can take precautions.

Understanding Skin Toxicity to Improve Patient Care

The various forms of skin toxicity reported in this study underscore the importance of understanding the potential side effects of TKIs. By being aware of these side effects, clinicians can provide better care for their patients, ensuring that they receive the benefits of these powerful drugs while minimizing the risks.

Dr.Camel's Conclusion

The study provides valuable information about the skin toxicity associated with TKIs, emphasizing the need for close monitoring and management of these side effects. This knowledge empowers clinicians to provide better care for their patients and ensure that they benefit from the advancements in lung cancer therapy while minimizing the risks.

Date :
  1. Date Completed n.d.
  2. Date Revised 2020-09-30
Further Info :

Pubmed ID

30976343

DOI: Digital Object Identifier

PMC6454160

Related Literature

SNS
PICO Info
in preparation
Languages

English

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