Paper Details 
Original Abstract of the Article :
A prospective study was initiated in 1979 to investigate the effect of hexamethylmelamine (HMM) as a second-line chemotherapeutic agent in the treatment of advanced adenocarcinoma of the ovary after failure of cisplatin-based multiple-agent chemotherapy. Of 20 evaluable patients, there were 5 patien...See full text at original site
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引用元:
https://doi.org/10.1016/0090-8258(87)90290-3

データ提供:米国国立医学図書館(NLM)

Hexamethylmelamine: A Potential Second-Line Treatment for Ovarian Cancer

The field of oncology is constantly searching for effective treatments for various types of cancer, especially those that are resistant to conventional therapies. This study delves into the efficacy of hexamethylmelamine (HMM) as a second-line chemotherapeutic agent for advanced ovarian cancer, specifically for patients who have not responded well to cisplatin-based chemotherapy. Researchers conducted a prospective study to investigate the impact of HMM on these patients, and their findings shed light on the potential benefits of this drug.

HMM Shows Promising Results for Ovarian Cancer

The study revealed a significant improvement in both progression-free interval and survival time for patients who responded to HMM treatment. Interestingly, the study also identified key factors that influence the effectiveness of HMM, such as performance status and the absence of measurable disease at the time of treatment initiation. These findings highlight the importance of individualized treatment approaches, taking into account the specific characteristics of each patient.

HMM: A Hope for Patients with Refractory Ovarian Cancer

The results suggest that HMM could be a valuable option for patients with ovarian cancer who have failed standard chemotherapy regimens. The study's findings provide a glimmer of hope for these patients, as HMM demonstrated the ability to induce complete responses, extend disease-free intervals, and prolong survival in a significant number of patients. The manageable side effects further support its potential as a viable treatment option.

Dr.Camel's Conclusion

Just like a camel navigates the vast desert, oncologists are constantly exploring new pathways to combat cancer. This research serves as a beacon, illuminating a potential route for treating advanced ovarian cancer with HMM. The findings are encouraging, but further investigation is needed to refine treatment protocols and tailor them to individual patient needs. It's important to note that this research offers a ray of hope for patients who are facing treatment challenges, reminding us that in the vast landscape of medicine, new solutions are always being discovered.

Date :
  1. Date Completed 1987-06-10
  2. Date Revised 2019-08-24
Further Info :

Pubmed ID

3106174

DOI: Digital Object Identifier

10.1016/0090-8258(87)90290-3

Related Literature

SNS
PICO Info
in preparation
Languages

English

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