Prophylactic use of exogenous melatonin and melatonin receptor agonists to improve sleep and delirium in the intensive care units: a systematic review and meta-analysis of randomized controlled trials.

Author: GaoFuqiang, LiZirong, SunWei, ZhangQingyu, ZhangShuai

Paper Details 
Original Abstract of the Article :
To investigate the efficacy of exogenous administration of melatonin and melatonin receptor agonists for the improvement of delirium, sleep, and other clinical outcomes of subjects in the intensive care unit (ICU). We carefully searched three electronic databases, i.e., Pubmed/Medline, Embase, and C...See full text at original site
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引用元:
https://doi.org/10.1007/s11325-019-01831-5

データ提供:米国国立医学図書館(NLM)

Melatonin: A Beacon of Hope in the Desert of ICU Sleep

This research explores the potential of melatonin and melatonin receptor agonists in improving sleep and reducing delirium in intensive care unit (ICU) patients. It’s like finding a beacon of hope in the vast desert of ICU care, where sleep and delirium can be major challenges. The authors conducted a systematic review and meta-analysis of eight randomized controlled trials that examined the effects of melatonin and melatonin receptor agonists in ICU patients. The results suggest that melatonin administration was associated with a trend towards longer sleep duration and fewer awakenings at night, leading to a significant reduction in the prevalence of delirium and a shorter ICU stay. The findings highlight the potential of melatonin as a valuable tool for improving patient outcomes in the ICU.

The Desert of ICU Care: Finding Sleep and Reducing Delirium

The study underscores the importance of addressing sleep and delirium in ICU patients, as they can have significant negative impacts on recovery and well-being. It’s like finding a well of water in a desert, providing a much-needed source of sustenance. The research points to melatonin as a potential solution for improving sleep quality and reducing delirium in this demanding environment.

Melatonin: A New Oasis in the Desert of ICU Care

This research offers hope for ICU patients who struggle with sleep and delirium. It’s like finding a new oasis in a vast desert, providing respite and restoring balance. The research suggests that melatonin could be a valuable tool for improving sleep quality and reducing delirium, leading to faster recovery and better patient outcomes.

Dr. Camel's Conclusion

This research provides valuable insights into the potential of melatonin for improving sleep and reducing delirium in ICU patients. It’s like finding a new path in a vast desert, offering hope for a brighter future. The study suggests that melatonin could be a valuable tool for improving patient care and promoting a more comfortable and peaceful recovery in the ICU.

Date :
  1. Date Completed 2021-01-13
  2. Date Revised 2021-01-13
Further Info :

Pubmed ID

31119597

DOI: Digital Object Identifier

10.1007/s11325-019-01831-5

Related Literature

SNS
PICO Info
in preparation
Languages

English

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