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Renal allograft loss due to renal vascular thrombosis in the US pediatric renal transplantation.

Author: GarroRouba, GeorgeRoshan P, GreenbaumLarry A, HoganJulien, PatelKavita, PatzerRachel E, WangChia-Shi, WarshawBarry, WinterbergPamela D

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

The incidence of allograft loss due to renal vascular thrombosis (RVT) has consistently declined among pediatric kidney transplants performed between 1995 and 2014. The decline was observed despite an increase in the prevalence of risk factors, such as en bloc kidney transplantation and prolonged cold ischemia time. The reasons for this improvement are unclear.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Renal vascular thrombosis (RVT) is a major cause of early allograft loss in the first year following pediatric kidney transplantation. We examined recent trends in allograft loss due to RVT and identified associated risk factors. METHODS: We identified 14,640 kidney-only transplants per...See full text at original site
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引用元：
https://doi.org/10.1007/s00467-019-04264-0

データ提供：米国国立医学図書館（NLM）

Renal Allograft Loss Due to Renal Vascular Thrombosis in the US Pediatric Renal Transplantation

This study delves into the critical area of pediatric nephrology, specifically investigating renal vascular thrombosis (RVT), a major cause of early allograft loss in pediatric kidney transplantation. The authors analyzed data from the US Renal Data System to examine trends in RVT-related allograft loss and identify associated risk factors.

Understanding Risk Factors in Pediatric Kidney Transplantation

The study reveals a significant decline in RVT-related allograft loss over time, but also identifies key risk factors, such as en bloc kidney transplantation and prolonged cold ischemia time. This research provides valuable insights into the factors that can influence transplant outcomes in pediatric patients.

Enhancing Transplant Success in Children

The study highlights the importance of minimizing risk factors and optimizing transplantation procedures to improve the long-term success of kidney transplantation in children.

Dr. Camel's Conclusion

This research, like a careful gardener nurturing a precious flower, provides essential insights into the delicate process of pediatric kidney transplantation. It sheds light on the factors that can influence transplant outcomes, ultimately helping to improve the lives of children awaiting this life-saving procedure.
Date :
  1. Date Completed 2020-07-06
  2. Date Revised 2020-07-06
Further Info :

Pubmed ID

31129729

DOI: Digital Object Identifier

10.1007/s00467-019-04264-0

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English

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