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Direct-Acting Antivirals for Hepatitis C: Predictors of Early Discontinuation in the Real World.
Author: AbrahamowiczMichal, BeauchampMarie-Eve, BernatskySasha, CarletonBruce, CurtisJeffrey R, FeldJordan, KleinMarina, WinthropKevin, de MouraCristiano Soares, de Ávila MachadoMarina Amaral
Original Abstract of the Article :
BACKGROUND: The treatment for hepatitis C virus (HCV) infection has evolved over time, and direct-acting antivirals (DAA) have revolutionized HCV therapy. OBJECTIVES: To (a) assess early treatment discontinuation and (b) identify predictors of early discontinuation in a cohort of patients receiving...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10397799/
データ提供:米国国立医学図書館(NLM)
Direct-Acting Antivirals: A Breakthrough in Hepatitis C Treatment
Hepatitis C virus (HCV) infection, a persistent foe that can lead to liver damage and cirrhosis, is like a relentless sandstorm that erodes the body's health. Direct-acting antivirals (DAAs), a new class of medications, have revolutionized the treatment of HCV infection, offering hope for a cure, much like a desert traveler discovering a safe haven from a raging sandstorm.A New Era of Hepatitis C Treatment
This study examines the real-world use of second-generation DAAs, analyzing discontinuation rates and identifying potential predictors of early treatment termination. The study found that DAAs were generally well-tolerated, with low rates of early discontinuation, a testament to the effectiveness and safety of this new treatment paradigm. It's like a desert traveler finding a reliable source of water, ensuring their journey can continue without interruption.Understanding Patient Factors
This study also highlights the importance of considering patient factors that could influence treatment adherence, like socioeconomic status, sex/gender, and pre-existing health conditions. It's like a wise desert traveler recognizing the importance of understanding the terrain and preparing accordingly. The study emphasizes the need for tailored approaches to HCV treatment, addressing the unique needs of each individual patient.Dr.Camel's Conclusion
This research provides valuable insights into the real-world use of direct-acting antivirals for hepatitis C, a critical step in the fight against this challenging disease. It's like discovering a hidden oasis in the desert, offering hope and a new perspective on managing this condition. The study highlights the importance of continued research and patient-centered approaches to ensure the best possible outcomes for individuals with HCV infection.Date :
- Date Completed 2019-12-02
- Date Revised 2023-08-05
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