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Efficacy and safety of a novel topical minocycline foam for the treatment of moderate to severe acne vulgaris: A phase 3 study.

Author: HooperDeirdre, JankicevicJasmina, KircikLeon, LainEdward, MooreAngela, RaoofTooraj Joseph, StuartIain, SullivanTory, ZaiacMartin

Clinical Trial, Phase IIIA Phase III trial is a trial that further rigorously verifies the efficacy and safety of a new drug or treatment, whose efficacy and safety have been confirmed in a Phase II trial, in a large number of patients, and evaluates whether it is superior to existing treatments.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

FMX101 4% topical minocycline foam proved to be effective and safe for the treatment of moderate to severe acne vulgaris (AV). A double-blind, vehicle-controlled study of 1488 participants found that the FMX101 4% group experienced significantly greater reductions in inflammatory lesion count and a higher rate of treatment success compared to the foam vehicle group.
Paper Details　
Original Abstract of the Article :
BACKGROUND: FMX101 4% topical minocycline foam has been shown to be an effective and safe treatment for acne vulgaris (AV). OBJECTIVE: To further evaluate the efficacy and safety of FMX101 4% in treating moderate to severe acne vulgaris. METHODS: A 12-week, multicenter, randomized (1:1), double-bl...See full text at original site
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引用元：
https://doi.org/10.1016/j.jaad.2019.05.078

データ提供：米国国立医学図書館（NLM）

Fighting Acne: A New Topical Treatment Shows Promise

Acne, a common skin condition, can have a significant impact on self-esteem. This research explores the efficacy and safety of a novel topical minocycline foam, FMX101 4%, for the treatment of moderate to severe acne.

A New Oasis in the Desert of Acne: Topical Minocycline Shows Promise

The study found that FMX101 4% topical minocycline foam significantly reduced inflammatory lesions and achieved a high rate of treatment success in patients with moderate to severe acne. Moreover, the foam was generally safe and well tolerated.

Navigating the Desert of Acne: Finding Clear Skin

This study offers a beacon of hope for those struggling with acne. The new topical minocycline foam provides a promising treatment option, offering the potential for clear skin and improved confidence.

Dr.Camel's Conclusion

This research suggests that FMX101 4% topical minocycline foam is an effective and safe treatment for moderate to severe acne. This new treatment option offers hope for clear skin and a renewed sense of confidence. It's like finding a refreshing oasis in the vast desert of acne.

Date :
  1. Date Completed 2020-11-17
  2. Date Revised 2020-11-17
Further Info :

Pubmed ID

31163231

DOI: Digital Object Identifier

10.1016/j.jaad.2019.05.078

Related Literature

Article Analysis
・Effects of minocycline topical
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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