Paper Details 
Original Abstract of the Article :
Vascular endothelial growth factor (VEGF), tyrosine kinase (TK) and mechanistic target of rapamycin kinase (mTOR) inhibitors are common first-line (1 L) treatments for metastatic renal cell carcinoma (mRCC). Despite treatment availability, the 5-year survival rate in patients diagnosed at the metast...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555983/

データ提供:米国国立医学図書館(NLM)

Real-World Treatment Patterns and Adverse Events in Metastatic Renal Cell Carcinoma

Metastatic renal cell carcinoma (mRCC) is a challenging disease to treat, like a stubborn sand dune that refuses to yield to the forces of medicine. This study takes a real-world look at the treatment patterns and adverse events associated with first-line therapies for mRCC. Researchers analyzed a large database of US claims to understand the current landscape of treatment for this disease, seeking to identify trends that could guide future clinical and scientific endeavors.

Understanding the Landscape of mRCC Treatment

The researchers observed that VEGF, TK, and mTOR inhibitors are commonly used as first-line treatments for mRCC. However, despite these treatment options, the five-year survival rate for patients diagnosed at the metastatic stage remains a mere 10%. This highlights the urgent need for novel and effective therapies. It's like searching for a hidden spring in the desert, a new approach that could dramatically improve survival rates.

Navigating Treatment Challenges

This study emphasizes the complexities of treating mRCC. While advancements in therapy are crucial, the need for ongoing research to improve outcomes is evident. It's a reminder that we must continue to explore new pathways in the vast desert of medical research, seeking solutions that can truly conquer this formidable disease.

Dr.Camel's Conclusion

This study provides a comprehensive overview of current treatment patterns and adverse events for metastatic renal cell carcinoma. It highlights the need for further research to develop new therapies and improve outcomes for patients with this challenging disease. The study also emphasizes the importance of understanding the real-world implications of treatment choices, as we continue to navigate the complex landscape of cancer care.

Date :
  1. Date Completed 2019-11-20
  2. Date Revised 2020-02-25
Further Info :

Pubmed ID

31174493

DOI: Digital Object Identifier

PMC6555983

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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