Development of an Indigo Naturalis Suppository for Topical Induction Therapy in Patients with Ulcerative Colitis.

Author: FukudaTomohiro, FukuharaKayoko, IwaoYasushi, KanaiTakanori, MikamiYohei, MizunoShinta, MutaguchiMakoto, NaganumaMakoto, NankiKosaku, NomuraEna, OgataHaruhiko, OnoKeiko, SugimotoShinya, SujinoTomohisa, TakabayashiKaoru, TanemotoShun, UmedaSatoko, YoshidaKosuke, YoshimatsuYusuke

Paper Details 
Original Abstract of the Article :
Indigo naturalis (IN) consists of ligands for the aryl hydrocarbon receptor and exhibits anti-inflammatory effects. Previously, we demonstrated that an 8-week treatment with oral IN is effective in inducing a clinical response in patients with ulcerative colitis (UC). Some UC patients with proctitis...See full text at original site
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引用元:
https://doi.org/10.1159/000501152

データ提供:米国国立医学図書館(NLM)

Developing a Topical Indigo Naturalis Suppository for Ulcerative Colitis: A New Oasis in the Desert of Inflammatory Bowel Disease

Ulcerative colitis (UC), a chronic inflammatory bowel disease, is like a persistent desert fire, causing pain, inflammation, and discomfort. This study, like a skilled desert firefighter, explores the potential of indigo naturalis (IN) in treating UC, seeking to develop a novel topical treatment for this debilitating condition.

The researchers, like resourceful desert engineers, have developed a topical IN suppository for patients with UC, hoping to target the inflammation directly and provide localized relief. They previously demonstrated the effectiveness of oral IN in inducing clinical response in patients with UC, but this new approach aims to deliver the therapeutic benefits directly to the inflamed area. The development of this suppository, like the construction of a well-placed oasis, holds promise for patients who are seeking a more targeted and localized treatment option.

A New Oasis in the Desert: Targeting Inflammation with Indigo Naturalis

This study offers a novel and promising approach to treating UC. The researchers' innovative development of a topical IN suppository suggests a potential alternative for patients who are refractory to conventional treatments. This research underscores the need for continued exploration of novel therapeutic approaches, seeking to find new oases of relief in the vast and often challenging desert of inflammatory bowel disease.

Health and Lifestyle Implications of Indigo Naturalis Therapy

Indigo naturalis therapy, like a desert oasis, offers hope for patients seeking relief from the chronic inflammation of UC. This study's development of a topical IN suppository suggests a potential new avenue for treatment, potentially improving the quality of life for patients with this debilitating condition. The research also emphasizes the importance of personalized approaches to UC management, seeking to find the most effective treatment strategies for each individual.

Dr.Camel's Conclusion

This study offers a glimpse into the future of UC treatment, showcasing the innovative potential of indigo naturalis. The development of a topical IN suppository represents a promising new approach, offering a targeted and localized therapy for patients seeking relief from this chronic inflammatory condition. Like a resourceful traveler who discovers a hidden oasis, researchers are constantly searching for new solutions, seeking to quench the thirst for better treatments in the vast and challenging desert of inflammatory bowel disease.

Date :
  1. Date Completed 2021-04-16
  2. Date Revised 2021-04-16
Further Info :

Pubmed ID

31238326

DOI: Digital Object Identifier

10.1159/000501152

Related Literature

SNS
PICO Info
in preparation
Languages

English

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