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A rare and severe cutaneous adverse effect of telaprevir: drug rash with eosinophilia and systemic symptoms.
Author: BahaliAnil G, Biyik OzkayaDilek, CengizFatma P, EmirogluNazan, OnsunNahide, SuOzlem
Original Abstract of the Article :
Telaprevir is a specific inhibitor of the hepatitis C (HCV) serine protease 3. Cutaneous side effects have been reported with telaprevir. Drug reaction with eosinophilia and systemic symptoms (DRESS) is a rare yet severe adverse drug-induced reaction characterized by exfoliative dermatitis and macul...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.23736/S0392-0488.17.05151-3
データ提供:米国国立医学図書館(NLM)
A Rare and Severe Cutaneous Adverse Effect of Telaprevir
In the vast desert of drug discovery, scientists are constantly seeking to identify and minimize potential adverse effects of medications. This case report describes a patient who developed a rare and severe cutaneous adverse effect, drug rash with eosinophilia and systemic symptoms (DRESS), following treatment with telaprevir, a medication used to treat hepatitis C. This is like encountering a rare desert creature that can be both beautiful and dangerous.
Telaprevir and DRESS
The patient developed a progressive diffuse, painful maculopapular exanthema, fever, facial edema, and lymphadenopathy after 11 weeks of treatment with telaprevir. This is like a sudden sandstorm that throws a traveler off course. The researchers concluded that telaprevir can cause severe skin reactions, emphasizing the importance of early diagnosis and treatment discontinuation.
Health Benefits and Lifestyle Implications
This case report serves as a reminder that even seemingly safe medications can have unexpected side effects. It's like navigating a desert where a seemingly benign oasis can hide a dangerous predator. This case underscores the importance of monitoring for adverse drug reactions and seeking immediate medical attention if any concerning symptoms develop.
Dr. Camel's Conclusion
This case report provides a valuable reminder of the potential risks associated with medication use. It's like navigating a desert where the path is not always straightforward. This case highlights the importance of being vigilant about potential adverse effects and seeking medical attention promptly if necessary. The researchers have done a great job of illustrating the complexities of drug therapy and the importance of careful monitoring for potential complications.
Date :
- Date Completed 2019-12-30
- Date Revised 2019-12-30
Further Info :
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