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Targeting CGRP and 5-HT<sub>1F</sub> Receptors for the Acute Therapy of Migraine: A Literature Review.

Author: ChanCalvin, GoadsbyPeter J, Moreno-AjonaDavid, Villar-MartínezMaría Dolores

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Emerging acute migraine treatments include CGRP receptor antagonists, gepants, and 5-HT1F receptor agonists. Phase III clinical trials of lasmiditan, rimegepant and ubrogepant met their primary endpoints, suggesting that the options for migraine-targeted acute therapy will soon increase.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To review and highlight current literature on emerging acute migraine treatments, focusing on CGRP receptor antagonists, gepants, and 5-HT BACKGROUND: Current acute migraine therapy consists of nonspecific analgesia and triptans. Limitations to these medicines, including lack of efficacy...See full text at original site
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引用元：
https://doi.org/10.1111/head.13582

データ提供：米国国立医学図書館（NLM）

Migraine Relief: Exploring New Frontiers in Treatment

This research dives into the complex and often debilitating world of migraine headaches. Imagine a desert, vast and relentless, with a sandstorm raging inside your head – that's what a migraine feels like. This study takes us on a journey through the latest advancements in migraine therapy, focusing on two promising targets: CGRP (calcitonin gene-related peptide) receptors and 5-HT1F receptors.

Targeting CGRP and 5-HT1F Receptors: A New Hope for Migraine Relief

This study highlights the potential of new drugs that target these receptors to provide relief from migraine attacks. It's like discovering a new oasis in the desert, a source of relief from the unrelenting pain. This research suggests that the future of migraine treatment is bright, with promising new therapies on the horizon.

Navigating the Migraine Landscape: A Guide to New Treatments

The study’s findings are particularly exciting for people with migraine who haven’t found relief with current medications. It offers a beacon of hope, suggesting that new treatments may soon be available. The study reminds us that the search for effective migraine therapies is ongoing and that new discoveries are constantly being made. It's like exploring a vast desert, with new landscapes and possibilities waiting to be uncovered.

Dr.Camel's Conclusion

This study offers a glimpse into the future of migraine treatment, with new targets and therapies on the horizon. It’s exciting to see the progress being made in this area and to know that new options are becoming available for those who suffer from migraines. This research underscores the importance of continuous research and innovation in addressing the challenges of migraine headaches.

Date :
  1. Date Completed 2020-07-20
  2. Date Revised 2020-07-20
Further Info :

Pubmed ID

31291016

DOI: Digital Object Identifier

10.1111/head.13582

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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