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Arthritis prevention in the pre-clinical phase of RA with abatacept (the APIPPRA study): a multi-centre, randomised, double-blind, parallel-group, placebo-controlled clinical trial protocol.
Author: AbrahamSonya, Al-LaithMariam, BosworthAisla, BruceIan N, BuckleyChristopher D, CiurtinCoziana, CopeAndrew P, D'AgostinoMaria-Antonietta, EmeryPaul, FilerAndrew, FisherBenjamin A, GastonHill, HoPauline, HuizingaThomas W J, IsaacsJohn D, JacklinClare, JasenecovaMarianna, KellyJoanna, LemppHeidi, McInnesIain B, MurphyCaroline, PrattArthur G, PrevostA Toby, RazaKarim, ShivapathamDharshene, TaylorPeter C, VasconcelosJoana C, WrightAlison J, van SchaardenburgDirkjan, ÖstorAndrew
Original Abstract of the Article :
We present a study protocol for a multi-centre, randomised, double-blind, parallel-group, placebo-controlled trial that seeks to test the feasibility, acceptability and effectiveness of a 52-week period of treatment with the first-in-class co-stimulatory blocker abatacept for preventing or delaying ...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6633323/
データ提供:米国国立医学図書館(NLM)
Abatacept: A Potential Oasis in the Desert of Rheumatoid Arthritis
This study delves into the complex world of rheumatoid arthritis (RA), a debilitating autoimmune disease that can feel as relentless as a sandstorm. The research focuses on abatacept, a groundbreaking medication that targets the immune system's ability to attack the body's own tissues, potentially preventing or delaying the onset of inflammatory arthritis. The study's primary objective is to assess the feasibility, acceptability, and effectiveness of abatacept in preventing the progression of RA in individuals at risk, offering a potential oasis in the desert of this challenging condition.Abatacept: A Promising New Approach to Rheumatoid Arthritis Prevention
The study aims to investigate the potential of abatacept as a preventive treatment for RA, offering a glimmer of hope in the desert of this chronic autoimmune disease. The research team seeks to determine whether abatacept can effectively halt or slow down the progression of RA in individuals at high risk, potentially reducing the long-term impact of this debilitating condition. The study's findings could have significant implications for the future management of RA, offering a potentially transformative approach to prevention and treatment.Navigating the Desert of Rheumatoid Arthritis
This research offers a potential new weapon in the fight against rheumatoid arthritis, providing hope for a future where individuals at risk can potentially prevent or delay the onset of this debilitating condition. It is important to note that this is a clinical trial protocol, and the results of the study are still pending. However, the study's design suggests a promising approach to RA prevention, potentially offering a new path through the desert of this challenging disease.Dr.Camel's Conclusion
This study explores the potential of abatacept as a preventive therapy for rheumatoid arthritis, offering a glimmer of hope in the desert of this complex autoimmune disease. The results of the study will be eagerly awaited, as they could lead to a new paradigm for managing and potentially preventing this debilitating condition.Date :
- Date Completed 2020-02-05
- Date Revised 2023-11-15
Further Info :
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