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[Pharmacological and clinical profiles of a novel calcimimetic, evocalcet (ORKEDIA<sup>®</sup>)].
Author: EndoYuichi, KawataTakehisa, TokunagaShin
Original Abstract of the Article :
Calcimimetics allosterically activate the calcium receptor (CaR) and inhibit the secretion of parathyroid hormone (PTH). Cinacalcet hydrochloride (cinacalcet) has been approved as the first calcimimetic drug for the treatment of secondary hyperparathyroidism (SHPT) in patients with hemodialysis. Cin...See full text at original site
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引用元:
https://doi.org/10.1254/fpj.154.35
データ提供:米国国立医学図書館(NLM)
A New Hope for Secondary Hyperparathyroidism: Introducing Evocalcet
This research explores the field of endocrinology, focusing on the treatment of secondary hyperparathyroidism (SHPT), a condition that affects patients with chronic kidney disease. The study introduces evocalcet, a novel calcimimetic drug, and compares its efficacy and safety to cinacalcet, the existing standard of care. This research utilizes a randomized, double-blind, head-to-head comparison study, a rigorous approach to assess the relative effectiveness and safety of two drugs.
A New Path to Treatment: Exploring the Potential of Evocalcet
The study demonstrates that evocalcet is as effective as cinacalcet in controlling PTH levels in patients with SHPT. The study also highlights that evocalcet has a better gastrointestinal safety profile than cinacalcet. This finding is like discovering a new oasis in the desert, offering a potential solution to the side effects associated with cinacalcet. Evocalcet could be a valuable alternative for patients who experience gastrointestinal side effects with cinacalcet.
Navigating the Desert of SHPT: Finding the Right Treatment
The study's findings could have significant implications for the management of SHPT. It provides evidence for the efficacy and safety of evocalcet, offering a potential alternative to cinacalcet. This knowledge is like a map leading us to a better understanding of SHPT treatment and a more informed decision-making process for clinicians and patients.
Dr. Camel's Conclusion
This research offers a beacon of hope for patients with SHPT. By introducing evocalcet, the study offers a new and potentially safer treatment option. This is like finding a new path through the desert, offering a more effective and tolerable approach to managing this challenging condition. As researchers and clinicians, we must continue to seek innovative solutions for treating endocrine disorders and improving the lives of our patients.
Date :
- Date Completed 2019-08-13
- Date Revised 2019-08-13
Further Info :
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