Verapamil and Cluster Headache: Still a Mystery. A Narrative Review of Efficacy, Mechanisms and Perspectives.

Author: BarloeseMads C J, JensenRigmor H, PetersenAnja S, SnoerAgneta, SoerensenAnne Mette S

Paper Details 
Original Abstract of the Article :
OBJECTIVE: A evaluation of the effect of verapamil and other calcium channel blockers in cluster headache (CH) treatment and an investigation of possible effect mechanisms. BACKGROUND: Verapamil has been used in the prevention of CH for almost 3 decades, however, the mode of action and therapeutic ...See full text at original site
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引用元:
https://doi.org/10.1111/head.13603

データ提供:米国国立医学図書館(NLM)

Verapamil and Cluster Headache: Unveiling the Mysteries of a Desert Storm

Cluster headache (CH), a debilitating neurological condition characterized by intense, recurring headaches, is a tempestuous desert storm. This study delves into the mysteries of verapamil, a calcium channel blocker, and its use in the prevention of CH. The authors conducted a narrative review of the literature, examining the efficacy, mechanisms, and future perspectives of verapamil in CH treatment. Their review reveals that verapamil has been used for almost three decades to prevent CH, but its precise mechanism of action remains unclear. The study highlights the need for further research to unravel the mysteries of verapamil's effectiveness in CH.

Verapamil: A Potential Solution for Cluster Headaches

The study's findings suggest that verapamil may be an effective prophylactic treatment for CH. While the precise mechanism of action remains unclear, clinical studies have shown that verapamil can reduce the frequency and severity of CH attacks. This research provides valuable insights into the potential of verapamil in treating CH, offering a promising avenue for further research and development.

Navigating the Complexities of Cluster Headaches

This research underscores the complexities of CH and the need for further research to understand the mechanisms of action of existing treatments. The study's findings highlight the importance of exploring new therapeutic options and uncovering the underlying mechanisms of disease to develop more effective treatment strategies.

Dr. Camel's Conclusion

The desert of CH is a harsh and relentless landscape. This research offers a glimpse into the potential of verapamil in mitigating its effects, but more research is needed to fully understand its mysteries. The study's findings highlight the need for continued exploration and innovation in the search for effective treatments for CH.

Date :
  1. Date Completed 2020-07-13
  2. Date Revised 2020-07-13
Further Info :

Pubmed ID

31339562

DOI: Digital Object Identifier

10.1111/head.13603

Related Literature

SNS
PICO Info
in preparation
Languages

English

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