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Efficacy and safety of 0.05% cyclosporine ophthalmic emulsion in treatment of Chinese patients with moderate to severe dry eye disease: A 12-week, multicenter, randomized, double-masked, placebo-controlled phase III clinical study.

Author: BianAiling, ChenDi, ChenWei, DengYingping, HongJing, ShaoYan, ZhangMingchang, ZhangShunhua, ZhaoJialiang

Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Clinical Trial, Phase IIIA Phase III trial is a trial that further rigorously verifies the efficacy and safety of a new drug or treatment, whose efficacy and safety have been confirmed in a Phase II trial, in a large number of patients, and evaluates whether it is superior to existing treatments.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study aims to compare the efficacy and safety profile of 0.05% cyclosporine ophthalmic emulsion (CsA OE) versus vehicle in Chinese patients with moderate to severe dry eye disease (DED). CsA OE is a long-standing treatment for DED in the US, but is not commercially available in China.
Paper Details　
Original Abstract of the Article :
Dry eye disease (DED) is a chronic ocular surface disease that affects hundreds of millions of people worldwide. Although 0.05% cyclosporine ophthalmic emulsion (CsA OE) has long been prescribed in the U.S. for the treatment of DED, it is not commercially available in China. Our study aims to compar...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709181/

データ提供：米国国立医学図書館（NLM）

Cyclosporine for Dry Eye Disease: A Promising Treatment for Chinese Patients

This study investigates the effectiveness and safety of 0.05% cyclosporine ophthalmic emulsion (CsA OE) in treating dry eye disease (DED) in Chinese patients. DED is a common condition that causes discomfort, blurry vision, and can significantly impact daily life. The study found that CsA OE was well-tolerated and effective in improving symptoms of DED in Chinese patients, offering hope for a new treatment option. This research is like a refreshing oasis in the desert of dry eye treatment, providing relief and improved vision for those suffering from this common condition.

CsA OE: A New Oasis for Dry Eye Patients

The study found that CsA OE was effective in improving symptoms of DED, such as dry eyes, blurry vision, and discomfort. This is like discovering a new oasis in the desert of dry eye treatment, providing relief and improved vision for those suffering from this common condition.

Treating Dry Eye: New Horizons in China

This study highlights the potential of CsA OE as an effective treatment for DED in Chinese patients. This is like finding a new path through the desert of dry eye treatment, opening up new possibilities for patients in China.

Dr.Camel's Conclusion

This study offers promising news for Chinese patients suffering from dry eye disease, demonstrating the effectiveness and safety of CsA OE in treating this condition. This research is a beacon of hope in the desert of dry eye treatment, offering a new path towards better vision and quality of life.

Date :
  1. Date Completed 2019-08-12
  2. Date Revised 2022-10-05
Further Info :

Pubmed ID

31374063

DOI: Digital Object Identifier

PMC6709181

Related Literature

Article Analysis
・Effects of cyclosporine ophthalmic
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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