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Preliminary examination of the orexin system on relapse-related factors in cocaine use disorder.
Author: FriesGabriel R, GreenCharles E, LaneScott D, MiguelGuadalupe G San, SchmitzJoy M, SuchtingRobert, VincentJessica N, WeaverMichael F, YoonJin H
Original Abstract of the Article :
RATIONALE: Current evidence and literature reviews provide a strong justification for examining the orexin receptor (OXR) system as a therapeutic target in substance use disorders, including cocaine and other psychostimulants. OBJECTIVES: In this preliminary, proof-of-concept examination of orexin ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/j.brainres.2019.146359
データ提供:米国国立医学図書館(NLM)
Orexin System: A Potential Target for Cocaine Use Disorder Treatment
Cocaine use disorder is a complex and challenging condition that can have devastating effects on individuals and families. This study examines the potential role of the orexin system in modulating relapse-related factors in cocaine use disorder. Researchers investigated the effects of suvorexant, an orexin receptor antagonist, on domains tied to relapse, including stress, sleep, cue reactivity, and inhibitory control. The study found that suvorexant showed promising results in reducing craving and improving sleep quality, suggesting its potential as a therapeutic agent for cocaine use disorder.
Targeting the Orexin System: A New Approach to Cocaine Use Disorder Treatment
This research delves into the potential of the orexin system as a target for treating cocaine use disorder. It’s like discovering a hidden pathway through a desert of addiction, offering a new avenue for reducing craving and promoting recovery. The study provides initial evidence for the effectiveness of orexin modulation in addressing relapse-related factors.
Developing Novel Therapies for Cocaine Use Disorder
The findings of this study highlight the need for further research into the orexin system and its potential therapeutic applications in cocaine use disorder. It’s like finding a promising oasis in the desert of addiction research, offering a potential source of hope for patients seeking recovery. The study underscores the importance of exploring novel therapeutic strategies to combat this challenging condition.
Dr.Camel's Conclusion
This study provides initial evidence for the potential of the orexin system as a target for treating cocaine use disorder. It’s like finding a new path through a challenging desert landscape, offering a glimmer of hope for patients struggling with addiction. The findings are encouraging for future research and development of novel therapies for cocaine use disorder.
Date :
- Date Completed 2021-06-07
- Date Revised 2021-06-07
Further Info :
Related Literature
English
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