Multi-targeted kinase inhibition alleviates mTOR inhibitor resistance in triple-negative breast cancer.

Author: FoekensJohn A, HeJichao, MartensJohn W M, McLaughlinRonan P, ZhangYinghui, van WestenGerard, van de WaterBob, van der NoordVera

Paper Details 
Original Abstract of the Article :
Owing to its genetic heterogeneity and acquired resistance, triple-negative breast cancer (TNBC) is not responsive to single-targeted therapy, causing disproportional cancer-related death worldwide. Combined targeted therapy strategies to block interactive oncogenic signaling networks are being expl...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797661/

データ提供:米国国立医学図書館(NLM)

Triple-Negative Breast Cancer: A Multi-Targeted Approach

Triple-negative breast cancer is a formidable foe, often resistant to traditional treatments. It's like a resilient desert plant that can withstand extreme conditions and outmaneuver conventional methods. This research explores the potential of a multi-targeted approach to combat this challenging type of cancer. Imagine using a combination of strategies to tackle a sandstorm—combining different types of barriers and wind deflectors to create a comprehensive defense. The authors are investigating how combining different targeted therapies can overcome the resistance of triple-negative breast cancer, offering hope for a more effective treatment strategy.

Overcoming Resistance: A Multi-Pronged Attack

This study presents a promising strategy for addressing the challenge of triple-negative breast cancer. Combining different targeted therapies offers a multi-pronged attack on the disease, potentially disrupting the intricate network of signals that allows cancer cells to survive and thrive. It's like using multiple layers of defense to protect a vulnerable oasis in the desert, effectively blocking the onslaught of a sandstorm.

Hope for Patients: A New Era of Personalized Treatment

This research provides hope for patients with triple-negative breast cancer, suggesting that a personalized, multi-targeted approach could be more effective than single-target therapies. It's like creating a customized shield to protect each traveler in the desert, tailoring the defense to their specific needs and vulnerabilities.

Dr.Camel's Conclusion

This study brings us closer to a more effective treatment for triple-negative breast cancer. It's like discovering a new weapon in the fight against this challenging disease, offering hope for a brighter future for those battling this formidable foe.

Date :
  1. Date Completed 2020-02-26
  2. Date Revised 2021-12-04
Further Info :

Pubmed ID

31388935

DOI: Digital Object Identifier

PMC6797661

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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