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Multi-targeted kinase inhibition alleviates mTOR inhibitor resistance in triple-negative breast cancer.
Author: FoekensJohn A, HeJichao, MartensJohn W M, McLaughlinRonan P, ZhangYinghui, van WestenGerard, van de WaterBob, van der NoordVera
Original Abstract of the Article :
Owing to its genetic heterogeneity and acquired resistance, triple-negative breast cancer (TNBC) is not responsive to single-targeted therapy, causing disproportional cancer-related death worldwide. Combined targeted therapy strategies to block interactive oncogenic signaling networks are being expl...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797661/
データ提供:米国国立医学図書館(NLM)
Triple-Negative Breast Cancer: A Multi-Targeted Approach
Triple-negative breast cancer is a formidable foe, often resistant to traditional treatments. It's like a resilient desert plant that can withstand extreme conditions and outmaneuver conventional methods. This research explores the potential of a multi-targeted approach to combat this challenging type of cancer. Imagine using a combination of strategies to tackle a sandstorm—combining different types of barriers and wind deflectors to create a comprehensive defense. The authors are investigating how combining different targeted therapies can overcome the resistance of triple-negative breast cancer, offering hope for a more effective treatment strategy.
Overcoming Resistance: A Multi-Pronged Attack
This study presents a promising strategy for addressing the challenge of triple-negative breast cancer. Combining different targeted therapies offers a multi-pronged attack on the disease, potentially disrupting the intricate network of signals that allows cancer cells to survive and thrive. It's like using multiple layers of defense to protect a vulnerable oasis in the desert, effectively blocking the onslaught of a sandstorm.
Hope for Patients: A New Era of Personalized Treatment
This research provides hope for patients with triple-negative breast cancer, suggesting that a personalized, multi-targeted approach could be more effective than single-target therapies. It's like creating a customized shield to protect each traveler in the desert, tailoring the defense to their specific needs and vulnerabilities.
Dr.Camel's Conclusion
This study brings us closer to a more effective treatment for triple-negative breast cancer. It's like discovering a new weapon in the fight against this challenging disease, offering hope for a brighter future for those battling this formidable foe.
Date :
- Date Completed 2020-02-26
- Date Revised 2021-12-04
Further Info :
Related Literature
English
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