Pazopanib efficacy and toxicity in a metastatic sarcoma cohort: Are Indian patients different?

Author: AggarwalAditi, BarwadAdarsh, DhamijaEkta, MridhaAsit Ranjan, PandeyRambha, RastogiSameer, SharmaAparna, VanidassaneIlavarasi

Paper Details 
Original Abstract of the Article :
PURPOSE: There is no study till date determining the spectrum of adverse events of pazopanib in Indian patients with advanced sarcoma. MATERIALS AND METHODS: We conducted a retrospective study by analyzing the case records of metastatic sarcoma patients treated with pazopanib from January 2016 to J...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.4103/ijc.IJC_105_18

データ提供:米国国立医学図書館(NLM)

Pazopanib's Effectiveness in Treating Metastatic Sarcoma: Are Indian Patients Different?

This study delves into the realm of cancer treatment, specifically investigating the use of pazopanib in patients with metastatic sarcoma. The researchers conducted a retrospective study, examining the medical records of patients treated with pazopanib in India. Their main goal was to understand the spectrum of adverse events experienced by these patients. The study found that Indian patients, while receiving lower dosages of pazopanib, experienced a different range of side effects compared to western populations. This discovery highlights the potential for variations in drug responses based on geographic location and genetic factors. The authors emphasize the need for further investigation to validate these findings through prospective studies.

Unveiling the Unique Toxicity Profile

This study reveals a fascinating discovery - Indian patients treated with pazopanib exhibit a distinct profile of adverse events compared to their western counterparts. This emphasizes the importance of considering individual factors, such as genetic background and geographic location, when prescribing medications. It's like observing different species of desert plants thriving in varied terrains - each with its own unique set of adaptations.

What Does This Mean for You?

While more research is needed, this study suggests that the side effects of pazopanib might differ depending on your geographic location. It's always best to discuss any concerns you have with your doctor and to ensure you're receiving the best possible care based on your individual needs. Remember, knowledge is power, and understanding your medications can help you navigate your health journey with confidence.

Dr.Camel's Conclusion

This research sheds light on the importance of understanding how medications might affect individuals differently based on their geographic location. It's a reminder that medicine is a complex science, and the journey to optimal treatment involves careful consideration of all factors. Just as a camel adapts to the harsh desert environment, our bodies also have unique ways of responding to medications. This research encourages further investigation to ensure that treatments are tailored to the specific needs of diverse populations.

Date :
  1. Date Completed 2020-01-09
  2. Date Revised 2021-12-04
Further Info :

Pubmed ID

31389382

DOI: Digital Object Identifier

10.4103/ijc.IJC_105_18

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.