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Gastrointestinal adverse effects of nintedanib and the associated risk factors in patients with idiopathic pulmonary fibrosis.
Author: IharaHiroaki, KatoMotoyasu, KurokawaKana, NakamuraTakahiro, OchiYusuke, SasakiShinichi, TakahashiFumiyuki, TakahashiKazuhisa, YamadaTomoko
Original Abstract of the Article :
Nausea and diarrhea are the most common adverse effects of nintedanib in patients with idiopathic pulmonary fibrosis (IPF). However, the clinical risk factors for these side effects remain unknown. In the present study, we investigated the characteristics of patients who developed gastrointestinal s...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700168/
データ提供:米国国立医学図書館(NLM)
Gastrointestinal Adverse Effects of Nintedanib in Idiopathic Pulmonary Fibrosis
The study of human health is a vast desert, filled with both oases of healing and perilous sandstorms of side effects. This research examines the gastrointestinal adverse effects of nintedanib, a drug used to treat idiopathic pulmonary fibrosis (IPF). Through a comprehensive analysis of patients receiving nintedanib, the authors identify clinical risk factors for nausea and diarrhea. The findings highlight the need for careful monitoring and management of gastrointestinal side effects in patients receiving this medication. A key finding is the association between low BMI, poor PS, and full dosage of nintedanib at treatment initiation with an increased risk of nausea. This research provides valuable insights for optimizing nintedanib treatment and mitigating potential complications.
Navigating the Side Effects of Nintedanib
The findings of this study highlight the importance of understanding the potential side effects of medications like nintedanib, especially in the treatment of complex conditions like IPF. The research underscores the need for close monitoring of patients receiving nintedanib, particularly those with low BMI, poor PS, and those initiating treatment with the full dosage. This information can empower clinicians to make informed decisions and optimize treatment regimens to minimize potential complications.
A Desert of Side Effects
This research serves as a reminder that the desert of medicine is not always a smooth and predictable path. The findings highlight the importance of carefully navigating the potential side effects of medications, particularly in the treatment of complex conditions like IPF. By understanding the nuances of nintedanib's gastrointestinal effects, clinicians can provide better care and improve patient outcomes.
Dr.Camel's Conclusion
This research, like a guidepost in a desert of potential side effects, sheds light on the gastrointestinal adverse effects of nintedanib in patients with IPF. The authors' meticulous examination of risk factors provides valuable insights for optimizing treatment strategies and mitigating potential complications. The findings encourage clinicians to tread carefully through the desert of side effects, always mindful of individual patient needs and the delicate balance between therapeutic benefits and potential risks.
Date :
- Date Completed 2020-11-02
- Date Revised 2021-01-10
Further Info :
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