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Long-term safety and efficacy of sarilumab plus methotrexate on disease activity, physical function and radiographic progression: 5 years of sarilumab plus methotrexate treatment.
Author: BurmesterGerd R, GenoveseMark C, Gómez-ReinoJuan José, KivitzAlan, LinYong, Maldonado-CoccoJosé Antonio, SerioloBruno, St JohnGregory, StanislavMarina, WangSheldon, van HoogstratenHubert, van der HeijdeDésirée
Original Abstract of the Article :
In MOBILITY (NCT01061736), sarilumab significantly reduced disease activity, improved physical function and inhibited radiographic progression at week 52 versus placebo in patients with rheumatoid arthritis (RA) and an inadequate response to methotrexate. We report 5-year safety, efficacy and radiog...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691511/
データ提供:米国国立医学図書館(NLM)
Long-Term Effects of Sarilumab Plus Methotrexate on Rheumatoid Arthritis
In the world of rheumatology, we're always seeking new ways to manage the challenging condition of rheumatoid arthritis (RA). This study focuses on the long-term impact of a combination therapy using sarilumab and methotrexate. It's like a two-pronged approach, using a biological drug (sarilumab) and a traditional medicine (methotrexate) to tackle RA. The researchers investigated the effectiveness of this treatment over five years, analyzing how it affected disease activity, physical function, and radiographic progression. They found that this combination therapy led to significant improvements in RA symptoms and even slowed down joint damage, offering hope for patients seeking long-term relief from RA. The results of this study demonstrate the potential for sarilumab plus methotrexate to be a valuable therapeutic option for patients with rheumatoid arthritis. It's like finding a hidden oasis in the vast desert of RA research, providing a promising path for treatment.A Beacon of Hope for Long-Term RA Management
The study's findings are promising, as they suggest that sarilumab plus methotrexate can effectively manage RA over an extended period. These results indicate that this combination therapy can provide long-term benefits, helping patients maintain a better quality of life while slowing down disease progression. It's like finding a durable and reliable camel to carry you through the challenging journey of managing rheumatoid arthritis.Living Well With Rheumatoid Arthritis
The researchers discovered that this combination therapy not only reduced disease activity but also improved physical function, which is crucial for people with RA. It's important for patients to actively engage in their treatment plan, maintain a healthy lifestyle, and listen to their bodies. These findings highlight the importance of staying proactive and working closely with medical professionals to find the best treatment options for managing RA and improving overall well-being. Think of it as finding the right compass to guide you on your journey to a healthier life with RA.Dr. Camel's Conclusion
The findings from this study offer a beacon of hope for patients with rheumatoid arthritis, suggesting that a combination of sarilumab and methotrexate may be an effective approach to managing the condition over the long term. This study highlights the need for continued research and exploration of innovative treatments that can improve the lives of individuals living with rheumatoid arthritis. Remember, even in the vast desert of RA research, there are promising oases of knowledge waiting to be discovered.Date :
- Date Completed 2020-04-28
- Date Revised 2020-04-28
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