Gingival Ischemia and Petechiae in a Patient Medicated With PCSK9 Inhibitor for Hypercholesterolemia: An Adverse Drug Event?

Author: ThermosGrigoris, TosiosKonstantinos I

Paper Details 
Original Abstract of the Article :
Monoclonal antibodies against proprotein-convertase subtilisin/kexin type 9 (PCSK9) inhibitors are a newly-introduced therapeutic approach against hypercholesterolemia. Clinical trials have reported few adverse effects of PCSK9 inhibitors and there are no reports of oral adverse effects. We present ...See full text at original site
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引用元:
https://doi.org/10.1002/cap.10043

データ提供:米国国立医学図書館(NLM)

Navigating the Desert of Unexpected Side Effects

This case report explores a potential adverse drug event associated with the use of PCSK9 inhibitors, a new class of drugs used to treat hypercholesterolemia. The authors, like skilled detectives investigating a medical mystery, present a case of a patient who experienced gingival discomfort, ischemia, and petechiae after receiving alirocumab, a PCSK9 inhibitor. This case highlights the importance of careful monitoring and understanding the potential side effects of new medications.

Unveiling the Hidden Dunes

This case report, like a discovery of a hidden oasis in the desert, reveals the potential for unexpected side effects with novel medications. It serves as a reminder that even with extensive clinical trials, new drugs can sometimes have unforeseen consequences.

A Call for Vigilance

This case report underscores the importance of vigilant monitoring for potential side effects, particularly when using new medications. Like a desert traveler who must be aware of the changing terrain, healthcare providers must be alert to any signs of adverse reactions. This case also highlights the need for ongoing research to fully understand the potential risks and benefits of novel medications.

Dr. Camel's Conclusion

This case report reminds us that the desert of drug development can be full of hidden dunes and unexpected challenges. It emphasizes the importance of careful monitoring and vigilance in the use of new medications, reminding us that even the most promising therapies can sometimes have unforeseen consequences.
Date :
  1. Date Completed 2019-12-09
  2. Date Revised 2021-12-04
Further Info :

Pubmed ID

31490035

DOI: Digital Object Identifier

10.1002/cap.10043

SNS
PICO Info
in preparation
Languages

English

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