Comparison of cytotoxicities and anti-allergic effects of topical ocular dual-action anti-allergic agents.

Author: FordjuorGladys, KimSung Il, LeeJi Eun, LeeJong Heon, LeeJong Soo, ParkChoul Yong

Paper Details 
Original Abstract of the Article :
BACKGROUND: To investigate the cytotoxicities of the topical ocular dual-action anti-allergic agents (alcaftadine 0.25%, bepotastine besilate 1.5%, and olopatadine HCL 0.1%) on human corneal epithelial cells (HCECs) and their anti-allergic effects on cultured conjunctival epithelial cells. METHODS:...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839072/

データ提供:米国国立医学図書館(NLM)

A Balancing Act: Balancing Efficacy and Safety in Ocular Anti-Allergic Agents

The quest for [effective treatment of ocular allergies] often involves a balancing act between [efficacy and safety]. This research investigates the [cytotoxicities and anti-allergic effects] of three topical ocular dual-action anti-allergic agents, aiming to find the right balance for patients.

Alcaftadine: A Promising Solution

The study's findings reveal that while all three agents exhibited anti-allergic effects, alcaftadine emerged as a promising candidate. Alcaftadine displayed the lowest cytotoxicity and the best wound healing properties compared to the other agents. This suggests that alcaftadine might be a better choice for patients with ocular surface risk factors, minimizing potential side effects.

Protecting the Eyes: Choosing the Right Anti-Allergic Agent

The study's findings highlight the importance of considering both efficacy and safety when choosing an anti-allergic agent for ocular allergies. Alcaftadine's lower cytotoxicity and effective anti-allergic properties make it a potential contender for addressing ocular allergies while minimizing potential risks.

Dr.Camel's Conclusion

The search for effective and safe solutions for ocular allergies is a constant endeavor. This study helps us navigate the desert of options, offering insights into the potential benefits and risks associated with different topical ocular dual-action anti-allergic agents. Alcaftadine's promising profile suggests that it might be a suitable choice for many patients, potentially leading to effective treatment with minimized side effects.

Date :
  1. Date Completed 2020-03-09
  2. Date Revised 2020-03-09
Further Info :

Pubmed ID

31703568

DOI: Digital Object Identifier

PMC6839072

SNS
PICO Info
in preparation
Languages

English

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