Bromelain Enhances the Anti-tumor Effects of Cisplatin on 4T1 Breast Tumor Model In Vivo.

Author: AbuNadiah, AlitheenNoorjahan Banu, MohamadNurul Elyani, YeapSwee Keong

Paper Details 
Original Abstract of the Article :
<b>Background:</b> This study aimed to evaluate the antitumor enhancing effect of bromelain consumption on 4T1-challenged mice treated with cisplatin. <b>Methods:</b> Mice challenged with 4T1 triple-negative breast cancer cells received water, bromelain, cisplatin, or bromelain + cisplatin treatmen...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876173/

データ提供:米国国立医学図書館(NLM)

Bromelain: A Potential Ally in the Fight Against Breast Cancer

Breast cancer, a devastating disease that affects millions of women, requires effective treatment options. This study investigates the potential of bromelain, a protein-digesting enzyme found in pineapples, to enhance the antitumor effects of cisplatin, a commonly used chemotherapy drug. The researchers explored the effects of bromelain alone and in combination with cisplatin on a mouse model of breast cancer. Their findings offer a promising avenue for improving cancer treatment.

Bromelain: A Desert Oasis of Anti-Cancer Properties

The study found that bromelain, when combined with cisplatin, significantly reduced tumor size and lung metastasis in mice with breast cancer. This synergistic effect is like discovering a hidden oasis in the desert of cancer research, offering a potential pathway for enhancing the effectiveness of chemotherapy. The study also revealed that bromelain alone had a positive impact, reducing tumor inflammation and immune suppression. This discovery suggests that bromelain could play a multi-faceted role in cancer treatment, not only by enhancing chemotherapy but also by modulating the tumor environment.

Unlocking Bromelain's Potential: A Journey Through the Desert

This research opens up new possibilities for using bromelain as a complementary therapy for breast cancer. The findings suggest that bromelain, like a rare desert flower, could hold valuable therapeutic potential. Further research is needed to understand the specific mechanisms by which bromelain enhances chemotherapy and to explore its potential in treating other types of cancer.

Dr. Camel's Conclusion

This study demonstrates the potential of bromelain to enhance the effectiveness of chemotherapy in treating breast cancer. The findings suggest that bromelain could offer a valuable therapeutic option for patients with breast cancer. As we continue to explore the vast desert of cancer research, we must remain open to innovative approaches that could lead to more effective treatments and improved outcomes for patients.
Date :
  1. Date Completed 2020-04-27
  2. Date Revised 2020-04-27
Further Info :

Pubmed ID

31752555

DOI: Digital Object Identifier

PMC6876173

Related Literature

SNS
PICO Info
in preparation
Languages

English

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