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A novel side effect of mitogen-activated protein kinase inhibitor cobimetinib: Acute corneal decompensation.
Author: AsfurogluMahmut, AsfuroğluYonca
Original Abstract of the Article :
A 38-year-old man with a diagnosis of BRAF-mutated metastatic melanoma was referred to our clinic. He had been under treatment with 60-mg oral cobimetinib daily for 21 days/7 day off in combination with 960 mg vemurafenib twice daily. The patient had symptoms of blurred vision and photophobia in his...See full text at original site
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896530/
データ提供:米国国立医学図書館(NLM)
Cobimetinib and Corneal Decompensation: A Novel Side Effect
The world of [oncology] is constantly evolving, with new therapies emerging to combat the challenges of cancer. This research delves into a novel side effect associated with the mitogen-activated protein kinase inhibitor cobimetinib, a medication used in combination with vemurafenib for the treatment of BRAF-mutated metastatic melanoma.Unveiling a New Side Effect
The study reports the case of a 38-year-old man who developed acute corneal decompensation, a condition characterized by clouding of the cornea, while undergoing treatment with cobimetinib and vemurafenib. This case highlights the importance of ongoing vigilance in monitoring patients for potential side effects, even those not previously described. This finding serves as a reminder that the desert of human physiology is vast and often holds unexpected secrets.Navigating the Unforeseen in Cancer Treatment
The study's findings underscore the importance of careful monitoring in cancer treatment, recognizing that even novel therapies can have unforeseen side effects. Just as a desert traveler must be prepared for unexpected storms and shifting sands, clinicians must remain alert to potential complications and be ready to adjust treatment plans as necessary. This case provides valuable insights into the complex interplay between medications and human physiology, guiding clinicians in the quest for optimal cancer treatment while minimizing potential risks.Dr. Camel's Conclusion
This case report expands our understanding of the potential side effects of cobimetinib, highlighting the importance of vigilant monitoring in cancer treatment. The study's findings serve as a reminder that the desert of human physiology is vast and full of surprises, and that careful observation is crucial in navigating the complex landscape of cancer therapy. The study encourages continued research into the long-term effects of cobimetinib and other cancer therapies, ensuring that patients receive the safest and most effective treatment possible.Date :
- Date Completed 2020-09-04
- Date Revised 2020-09-04
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