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Expert Consensus on the Management of Adverse Events During Treatment with Lenvatinib for Thyroid Cancer.

Author: GerrardG, GlenH, GoodJ, LeiM, LyonA R, NewboldK, ReedN, StrachanM, WadsleyJ

Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Consensus-based guidance for the routine management of adverse events associated with lenvatinib is recommended. Prophylaxis, regular monitoring, and symptomatic management with appropriate short treatment breaks and dose reductions for persistent adverse events are suggested to enable patients to remain on the optimal dose regimen.
Paper Details　
Original Abstract of the Article :
AIMS: Lenvatinib is an oral multi-kinase inhibitor approved for the treatment of adults with progressive, locally advanced or metastatic, differentiated thyroid carcinoma refractory to radioactive iodine. MATERIALS AND METHODS: A literature review was undertaken to inform the development of consens...See full text at original site
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引用元：
https://doi.org/10.1016/j.clon.2019.11.010

データ提供：米国国立医学図書館（NLM）

Lenvatinib: Managing Adverse Events in Thyroid Cancer Treatment

Lenvatinib, a targeted therapy for thyroid cancer, is a powerful tool but can also cause side effects. This research explores the management of common adverse events associated with lenvatinib, offering practical guidance for healthcare providers. The study provides a consensus-based approach to address these challenges and ensure optimal patient care during treatment.

A Desert Oasis of Care: Managing Lenvatinib-Related Adverse Events

The study highlights the importance of proactive management strategies for lenvatinib-related adverse events, such as hypertension, diarrhea, weight loss, skin toxicities, and cardiovascular events. It outlines specific recommendations for managing these side effects, including medication adjustments, treatment breaks, and lifestyle modifications. This research emphasizes the need for close monitoring and individualized care to ensure the safety and effectiveness of lenvatinib therapy.

Navigating the Side Effects: Ensuring Patient Well-being during Lenvatinib Treatment

This research provides a valuable roadmap for healthcare professionals managing lenvatinib therapy. It emphasizes the importance of anticipating and addressing potential side effects, ensuring a smooth and successful treatment journey for patients. Just as a desert traveler must be prepared for the challenges of the journey, healthcare providers must be equipped to navigate the potential side effects of lenvatinib, ensuring the well-being of their patients.

Dr.Camel's Conclusion

This research offers a comprehensive approach to managing adverse events associated with lenvatinib therapy, providing essential guidance for healthcare providers. By understanding the potential side effects and implementing proactive management strategies, we can ensure a safer and more effective treatment experience for patients battling thyroid cancer.

Date :
  1. Date Completed 2021-05-24
  2. Date Revised 2021-05-24
Further Info :

Pubmed ID

31843241

DOI: Digital Object Identifier

10.1016/j.clon.2019.11.010

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