Effect of phosphodiesterase-5 inhibitors (PDE5is) on the treatment of male infertility: A protocol for systematic review and meta-analysis.

Author: DongLiang, LiYulin, ShenYifeng, YanXuhong, YuXujun, ZhangXiaojin

Paper Details 
Original Abstract of the Article :
Male infertility is a worldwide problem with limitations in the treatment. Phosphodiesterase-5 inhibitors (PDE5is) is the first choice for the treatment of erectile dysfunction (ED), but more and more studies show that it has a certain effect on male infertility in recent years. The literatures of P...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6922501/

データ提供:米国国立医学図書館(NLM)

Phosphodiesterase-5 Inhibitors (PDE5is) and Male Infertility: A Systematic Review and Meta-analysis

The field of [reproductive medicine] is continuously striving to understand and address the challenges of infertility. This research focuses on the potential role of phosphodiesterase-5 inhibitors (PDE5is), commonly used to treat erectile dysfunction, in the treatment of male infertility. The study aims to conduct a systematic review and meta-analysis to evaluate the effects of PDE5is on semen quality in men with infertility. The findings could provide valuable insights into the potential benefits and limitations of PDE5is in managing male infertility, contributing to the development of more effective treatments for this prevalent condition.

PDE5is: A Potential Tool for Treating Male Infertility

The study explores the potential of PDE5is, commonly used to treat erectile dysfunction, in the management of male infertility. While PDE5is have shown promise in improving semen quality in some studies, the evidence remains inconsistent. This systematic review and meta-analysis aim to provide a comprehensive assessment of the effects of PDE5is on semen quality in men with infertility, potentially clarifying the role of these drugs in managing this complex condition. The findings could guide clinical decision-making and inform future research into the use of PDE5is in male infertility.

Navigating the Complexities of Male Infertility

Male infertility is a complex issue, often requiring a multi-faceted approach to treatment. This research highlights the importance of exploring new avenues for managing this condition. The systematic review and meta-analysis of PDE5is could provide valuable insights into the potential benefits and limitations of these drugs in improving semen quality in men with infertility. Just as a camel navigates a challenging desert landscape, researchers are working tirelessly to find solutions for improving reproductive health and addressing the challenges of infertility.

Dr.Camel's Conclusion

The study aims to provide a comprehensive assessment of the potential role of PDE5is in treating male infertility. This systematic review and meta-analysis could offer valuable insights into the effects of PDE5is on semen quality, potentially clarifying the role of these drugs in managing this complex condition. Just as a camel relies on its instincts to navigate the desert, researchers are using their expertise to navigate the complexities of infertility, seeking new and effective treatment approaches to improve reproductive health.

Date :
  1. Date Completed 2019-12-25
  2. Date Revised 2023-09-05
Further Info :

Pubmed ID

31852117

DOI: Digital Object Identifier

PMC6922501

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Languages

English

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