Comparative effects of 18 antipsychotics on metabolic function in patients with schizophrenia, predictors of metabolic dysregulation, and association with psychopathology: a systematic review and network meta-analysis.

Author: ArumuhamAtheeshaan, BeckKatherine, CiprianiAndrea, EfthimiouOrestis, HindleyGuy, HowesOliver D, McCutcheonRobert A, MizunoYuya, NatesanSridhar, PillingerToby, VanoLuke

Paper Details 
Original Abstract of the Article :
Antipsychotic treatment is associated with metabolic disturbance. However, the degree to which metabolic alterations occur in treatment with different antipsychotics is unclear. Predictors of metabolic dysregulation are poorly understood and the association between metabolic change and change in psy...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029416/

データ提供:米国国立医学図書館(NLM)

Metabolic Side Effects of Antipsychotic Medications: A Comprehensive Review

This study meticulously analyzed the metabolic side effects of 18 different antipsychotic medications used to treat schizophrenia. The authors conducted a systematic review and network meta-analysis, synthesizing and comparing the results of numerous studies to provide a comprehensive overview of the metabolic effects of these medications. The researchers were interested in understanding the varying effects of these medications on metabolism, identifying factors that could predict metabolic dysregulation, and exploring the relationship between changes in metabolic parameters and improvements in psychiatric symptoms. This study provides a valuable resource for clinicians treating schizophrenia, enabling them to make informed decisions about antipsychotic medication selection while minimizing the potential for metabolic complications.

Antipsychotic Medications: Weighing Benefits and Risks

This study provides valuable insights into the metabolic risks associated with different antipsychotic medications. The research found that antipsychotic medications can lead to metabolic disturbances, and the severity of these disturbances varies depending on the specific medication used. The findings highlight the need for careful monitoring of metabolic parameters in patients taking antipsychotic medications to ensure their safety and well-being.

Managing Metabolic Risks: A Collaborative Approach

This research reinforces the importance of a collaborative approach to managing the metabolic risks associated with antipsychotic medications. Clinicians should carefully consider the potential metabolic side effects of different medications and work with patients to develop individualized treatment plans. Regular monitoring of metabolic parameters, lifestyle modifications, and the use of other medications to manage metabolic complications are all important components of this collaborative approach. This study reminds us that the journey of patient care is a desert trek, where we must navigate challenges and work together to find solutions.

Dr.Camel's Conclusion

This study provides a comprehensive review of the metabolic effects of antipsychotic medications. It highlights the importance of considering metabolic risks when prescribing antipsychotic medications, particularly in the context of schizophrenia treatment. The findings emphasize the need for careful monitoring and a collaborative approach to managing these risks.
Date :
  1. Date Completed 2020-01-24
  2. Date Revised 2023-01-18
Further Info :

Pubmed ID

31860457

DOI: Digital Object Identifier

PMC7029416

Related Literature

SNS
PICO Info
in preparation
Languages

English

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