Carryover effects of baloxavir acid in human nasopharyngeal/pharyngeal swabs on infectious titer testing of influenza virus.

Author: BabaKeiko, IshibashiToru, KawaguchiKeiko, NaitoAkira, NoshiTakeshi, OkaRyoko, OmotoShinya, ShanoShinya, ShishidoTakao, UeharaTakeki

Paper Details 
Original Abstract of the Article :
Baloxavir marboxil (BXM) demonstrated a rapid and profound decline in infectious viral titer 1 day after BXM administration. Rapid reduction in virus titer is a characteristic of BXM. There may be a possibility that drug carryover effects have impacts on the observed antiviral effects due to the poo...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182602/

データ提供:米国国立医学図書館(NLM)

Baloxavir Acid: A Promising Antiviral with Carryover Effects

This study investigates the carryover effects of baloxavir acid (BXA), an antiviral drug used to treat influenza, on infectious titer testing. The researchers found that BXA has a rapid and profound decline in infectious viral titer one day after administration, which is a characteristic of this drug. However, they also noted that there might be possible carryover effects of BXA on infectious titer testing. To investigate this, they evaluated the impact of BXA on viral titer reduction and symptom alleviation. The study found that BXA carryover had little impact on infectious titer testing.

Baloxavir Acid's Effectiveness in Influenze Treatment

This study provides valuable information about the effectiveness of baloxavir acid in treating influenza. The researchers found that the drug has a rapid and profound decline in infectious viral titer, indicating its potential for quickly reducing viral load. Furthermore, the minimal impact of carryover effects on infectious titer testing suggests that BXA is a reliable tool for measuring viral activity.

Understanding the Dynamics of Antiviral Treatment

This study underscores the importance of understanding the dynamics of antiviral treatment, including potential carryover effects. As with any medication, it's essential to consider how the drug interacts with the body over time and to evaluate its impact on diagnostic tests.

Dr. Camel's Conclusion

Like a desert wind that carries seeds and disperses them across the landscape, antiviral drugs like baloxavir acid can have complex effects on the body. This research provides valuable insights into the dynamics of BXA, helping healthcare professionals to better understand its potential for treating influenza.

Date :
  1. Date Completed 2021-02-18
  2. Date Revised 2021-02-18
Further Info :

Pubmed ID

31994309

DOI: Digital Object Identifier

PMC7182602

Related Literature

SNS
PICO Info
in preparation
Languages

English

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