Paper Details

  1. Home
  2. Paper Details

Characterization of adverse reactions to benznidazole in patients with Chagas disease in the Federal District, Brazil.

Author: ArrudaHilda Maria Benevides da Silva de, GontijoMaria Katarine Costa Lucas, NoronhaElza Ferreira, ToledoMaria Inês de

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Observational StudyResearch that observes and collects data on participants' behavior and outcomes in their natural state, without intervention.

Overview

Benznidazole treatment for Chagas disease was associated with a high incidence of adverse drug reactions, leading to treatment discontinuation in a significant number of patients.
Paper Details　
Original Abstract of the Article :
INTRODUCTION: Benznidazole is used for treating Chagas disease (CD). This cross-sectional study aimed to characterize the adverse drug reactions (ADRs) of benznidazole at a public hospital in Brazil's Federal District. METHODS: Medical records were analyzed and ADRs were categorized by type, intens...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083386/

データ提供：米国国立医学図書館（NLM）

Addressing Adverse Reactions to Benznidazole: A Challenge in Chagas Disease Treatment

Chagas disease, a parasitic infection primarily affecting Latin America, poses a significant challenge to global health. Benznidazole, the primary drug used to treat Chagas, can lead to adverse drug reactions (ADRs). This study aimed to characterize these ADRs in a population of patients receiving benznidazole treatment in Brazil.

Understanding the Side Effects

The study revealed a high incidence of ADRs, with a significant number of patients discontinuing treatment due to these reactions. This highlights the urgent need for alternative treatment options that are safer and more tolerable for patients with Chagas disease.

Seeking Safer Alternatives

This research underscores the importance of optimizing Chagas disease treatment strategies to minimize ADRs and improve patient outcomes. Like a camel seeking a cool oasis in the desert, researchers are continuously searching for safer and more effective ways to combat this debilitating disease.

Dr.Camel's Conclusion

This study provides a comprehensive analysis of adverse drug reactions associated with benznidazole, the primary drug used to treat Chagas disease. The findings underscore the need for safer and more effective treatments for this neglected tropical disease.

Date :
  1. Date Completed 2020-03-23
  2. Date Revised 2023-11-13
Further Info :

Pubmed ID

31994658

DOI: Digital Object Identifier

PMC7083386

Related Literature

Article Analysis
・Side Effects of benznidazole
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.