Evaluation of Mortality During Long-Term Treatment with Tafamidis for Transthyretin Amyloidosis with Polyneuropathy: Clinical Trial Results up to 8.5 Years.

Author: CoelhoTeresa, EbedeBen, LiHuihua, MerliniGiampaolo, StewartMichelle, Waddington CruzMárcia

Paper Details 
Original Abstract of the Article :
INTRODUCTION: The effects of tafamidis on mortality in Val30Met and non-Val30Met patients with transthyretin amyloidosis with polyneuropathy (ATTR-PN) were evaluated. METHODS: The analyses were based on cumulative data from the Val30Met patients in the 18-month double-blind registration study and i...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229124/

データ提供:米国国立医学図書館(NLM)

Evaluation of Mortality During Long-Term Treatment with Tafamidis for Transthyretin Amyloidosis with Polyneuropathy: Clinical Trial Results up to 8.5 Years

As a researcher, I am always intrigued by studies that explore the long-term effects of treatment. This study delves into the impact of tafamidis on mortality in patients with transthyretin amyloidosis with polyneuropathy (ATTR-PN) over an extended period.

The researchers analyzed data from clinical trials involving patients with ATTR-PN, a rare disease that affects the nervous system. They found that long-term tafamidis treatment may confer a survival benefit in these patients. The data showed a significant difference in survival between patients who received tafamidis and those who received placebo, particularly in the Val30Met group. These findings provide valuable insights into the potential long-term benefits of tafamidis treatment for ATTR-PN.

A Potential Long-Term Survival Benefit for ATTR-PN Patients

This study suggests that tafamidis may offer a potential long-term survival benefit for patients with ATTR-PN. The findings highlight the importance of continued research into effective therapies for this rare and challenging condition. These results provide hope for patients with ATTR-PN and their families, offering the potential for improved survival and quality of life.

Understanding the Long-Term Implications of Tafamidis Treatment

While this study offers promising results, it is important to consider the long-term implications of tafamidis treatment. Further research is needed to fully understand the long-term benefits and risks of this medication. This study serves as a valuable foundation for future research that will help refine our understanding of ATTR-PN and the potential of tafamidis as a therapeutic option.

Dr.Camel's Conclusion

Just as a camel needs to be prepared for the long journey through the desert, researchers need to be dedicated to understanding the long-term effects of treatments. This study provides valuable insights into the potential long-term benefits of tafamidis for ATTR-PN, but it's important to continue researching and monitoring the long-term effects of this medication.

Date :
  1. Date Completed n.d.
  2. Date Revised 2020-09-28
Further Info :

Pubmed ID

32107748

DOI: Digital Object Identifier

PMC7229124

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