A Novel Drug Delivery Carrier Comprised of Nimodipine Drug Solution and a Nanoemulsion: Preparation, Characterization, in vitro, and in vivo Studies.

Author: ChenJianming, DaiQi, FuZhiqin, GuYongwei, HuangSaixu, HuangZhiyong, RenFuzheng, ShiYamin, TangShuyan, WuXin, XuYoufa

Paper Details 
Original Abstract of the Article :
Nimodipine (NIMO) is used clinically to treat ischemic damage resulting from subarachnoid hemorrhage. However, clinical application of NIMO is limited by poor aqueous solubility and low safety. To overcome these limitations, a novel two-vial NIMO-loaded nanoemulsion (NIMO-TNE) was designed in this s...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036601/

データ提供:米国国立医学図書館(NLM)

Nimodipine Nanoemulsion: A Novel Oasis in the Treatment of Ischemic Damage

Ischemic damage, like a harsh desert wind, can inflict serious harm, particularly in cases of subarachnoid hemorrhage. This research explores a novel approach to delivering nimodipine, a promising medication, to treat ischemic damage. The study aims to develop and evaluate a new formulation of nimodipine, a nanoemulsion, that could improve its delivery and efficacy. The researchers found that the nanoemulsion formulation of nimodipine showed promise in improving its delivery and effectiveness, potentially offering a more effective treatment approach for ischemic damage.

Nimodipine Nanoemulsion: A New Oasis for Ischemic Damage

This study highlights the potential of a novel nanoemulsion formulation of nimodipine to improve its delivery and efficacy in treating ischemic damage, offering a potential solution for patients facing this challenging condition.

Navigating the Desert of Ischemic Damage: Finding Effective Treatments

The findings suggest that the nanoemulsion formulation of nimodipine could offer a more effective oasis for patients facing ischemic damage, potentially improving treatment outcomes and quality of life. This research underscores the importance of exploring innovative delivery approaches to enhance the efficacy of existing medications.

Dr.Camel's Conclusion

The desert of ischemic damage can be a harsh and unforgiving place. This study offers a glimmer of hope with a novel nanoemulsion formulation of nimodipine, like a refreshing oasis, that could provide a more effective treatment approach for patients facing this condition. This research could lead to a brighter future for those affected by ischemic damage, offering a path toward a healthier and more fulfilling life.

Date :
  1. Date Completed 2020-06-29
  2. Date Revised 2022-04-13
Further Info :

Pubmed ID

32110014

DOI: Digital Object Identifier

PMC7036601

Related Literature

SNS
PICO Info
in preparation
Languages

English

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