Methylnaltrexone and Naloxone for Opioid-induced Constipation in the Critical Care Setting.

Author: AlviZara, ElsharkawyBasant, SainiHarneel S, SinghBavandeep, YasirMuhammad

Paper Details 
Original Abstract of the Article :
Opioid antagonists in the ICU are often a last-line medication given to patients with opioid-induced constipation. Traditionally, patients have been administered nonopioid-based bowel regimens such as senna, peg, and docusate to treat constipation. Despite the obvious need to treat acute pain with o...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7051104/

データ提供:米国国立医学図書館(NLM)

Navigating the Desert of Opioid-Induced Constipation

Opioids are a valuable tool for pain management, but they often come with a challenging side effect – constipation. This research explores the use of naloxone and methylnaltrexone (MNTX) to alleviate opioid-induced constipation in critically ill patients, a condition that can lead to serious complications. It's like a camel navigating a desert of discomfort, seeking relief from the burden of constipation.

The study examines the efficacy of naloxone and methylnaltrexone (MNTX) in relieving opioid-induced constipation and preventing gastrointestinal complications in critical care settings. The findings highlight the importance of treating constipation, which can significantly impact patient recovery. The research is like finding a path through a treacherous desert, guiding clinicians towards safer and more effective treatment options.

Easing the Burden of Opioid-Induced Constipation

This study emphasizes the importance of addressing opioid-induced constipation, a common side effect that can lead to serious complications in critical care settings. The findings suggest that naloxone and methylnaltrexone (MNTX) can play a significant role in relieving constipation and improving patient outcomes. This research is like a refreshing spring in the desert, offering relief from the discomfort of opioid-induced constipation.

The Importance of Constipation Management in Critical Care

This research highlights the need for effective management of opioid-induced constipation, especially in critically ill patients. The findings provide valuable insights into the use of naloxone and methylnaltrexone (MNTX) in treating this challenging condition. It's like finding a guide who can help you navigate the difficult terrain of opioid-induced constipation.

Dr.Camel's Conclusion

This study emphasizes the importance of managing opioid-induced constipation in critically ill patients to prevent complications and improve patient outcomes. The research provides valuable insights into the use of naloxone and methylnaltrexone (MNTX) as effective treatment options, offering a glimmer of hope in the desert of opioid-related constipation.

Date :
  1. Date Completed n.d.
  2. Date Revised 2020-09-28
Further Info :

Pubmed ID

32181073

DOI: Digital Object Identifier

PMC7051104

Related Literature

SNS
PICO Info
in preparation
Languages

English

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