Paper Details 
Original Abstract of the Article :
INTRODUCTION: We investigated the sexually dimorphic effects of Dextromethorphan (DM) on cognitive and depression-like behaviors as well as on hippocampal histology in rats following acute administration. METHODS: Wistar rats of both sexes were treated with 25 or 50 mg/kg of DM for 7 days via intra...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7101514/

データ提供:米国国立医学図書館(NLM)

Dextromethorphan: A Desert Oasis or a Shifting Mirage?

Dextromethorphan, a common cough suppressant, has sparked interest in its potential effects on mood and cognitive function. This study delves into the effects of dextromethorphan on rats, exploring how this substance influences behaviors associated with depression and cognitive function. Think of this study as exploring the effects of a desert traveler's encounter with an oasis - a place of potential respite or unexpected challenges.

The researchers meticulously observed how dextromethorphan affected the rats' behavior, using tests designed to assess depression-like behavior and cognitive abilities. They found that dextromethorphan seemed to increase immobility time in the Tail Suspension Test (TST) in male rats, indicating a potential depressive effect. However, it also impaired cognitive function in both male and female rats.

This study reveals that dextromethorphan, like a desert oasis that can be both a refuge and a source of unforeseen consequences, may have different effects depending on the individual and the specific behaviors being assessed.

Unveiling the Complexities of Dextromethorphan

This study highlights the complex effects of dextromethorphan on mood and cognitive function, emphasizing the importance of considering individual differences and potential risks associated with its use.

The Importance of Careful Consideration of Medications

This study serves as a reminder that even seemingly harmless medications can have unexpected effects. It's like venturing into the desert, where a seemingly safe oasis can harbor hidden dangers. It reinforces the importance of carefully considering the potential benefits and risks associated with medications.

Dr.Camel's Conclusion

Dextromethorphan, a common cough suppressant, may have a complex and potentially paradoxical impact on mood and cognitive function. This study highlights the importance of further research to understand the nuances of this substance and its potential effects on individuals.

Date :
  1. Date Completed n.d.
  2. Date Revised 2022-04-13
Further Info :

Pubmed ID

32231776

DOI: Digital Object Identifier

PMC7101514

Related Literature

SNS
PICO Info
in preparation
Languages

English

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