A Systematic Review and Network Meta-analysis of Novel Androgen Receptor Inhibitors in Non-metastatic Castration-resistant Prostate Cancer.

Author: BhindiBimal, ChandrasekarThenappan, FleshnerNeil, GoldbergHanan, HirdAmanda E, KlaassenZachary, KlotzLaurence, MageeDiana E, SatkunasivamRaj, WallisChristopher J D, YeXiang Y

Paper Details 
Original Abstract of the Article :
Among men with high-risk non-metastatic castrate-resistant prostate cancer (nmCRPC), we used network meta-analysis to compare non-steroidal anti-androgens (NSAAs) and stratified class-level meta-analysis to identify subgroups with particular benefit from NSAAs with androgen deprivation therapy versu...See full text at original site
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引用元:
https://doi.org/10.1016/j.clgc.2020.02.005

データ提供:米国国立医学図書館(NLM)

Novel Androgen Receptor Inhibitors: A New Path Through the Desert of Prostate Cancer

Prostate cancer is a serious disease, a formidable foe that can disrupt lives. Finding effective treatments can feel like searching for an oasis in the vast and unforgiving desert of cancer. This study explores the potential of novel androgen receptor inhibitors, a new class of medication, in treating non-metastatic castration-resistant prostate cancer (nmCRPC). It's like discovering a new trail through the desert, offering a potentially more effective way to combat this disease.

The researchers conducted a network meta-analysis, a comprehensive approach that allows them to compare the effectiveness of different androgen receptor inhibitors. They found that these inhibitors, when combined with androgen deprivation therapy, were more effective than androgen deprivation therapy alone in treating nmCRPC. It's like finding a more reliable camel for traversing the challenging terrain of prostate cancer, offering a potentially better chance of survival and a better quality of life.

A Beacon of Hope in the Desert of Prostate Cancer: A New Path to Treatment

This study offers a glimmer of hope in the desert of prostate cancer, highlighting the potential of novel androgen receptor inhibitors as a valuable treatment option for men with nmCRPC. It's a reminder that even in the face of this formidable foe, there are often new avenues of treatment to explore. The study's findings suggest that these inhibitors could significantly improve outcomes for patients with nmCRPC.

Navigating the Desert of Prostate Cancer: A Journey Toward Recovery

Prostate cancer can be a daunting journey, like navigating a vast and unforgiving desert. This study offers a new path through this challenging landscape, highlighting the potential of novel androgen receptor inhibitors to improve outcomes for patients with nmCRPC. It's a reminder that even in the face of this formidable foe, there is often hope to be found.

Dr. Camel's Conclusion

This study, like a wellspring of knowledge in the desert, offers valuable insights into the potential of novel androgen receptor inhibitors for treating men with nmCRPC. It's a reminder that even in the most challenging landscapes, there are often new avenues of treatment to explore.

Date :
  1. Date Completed 2021-08-18
  2. Date Revised 2021-08-18
Further Info :

Pubmed ID

32278840

DOI: Digital Object Identifier

10.1016/j.clgc.2020.02.005

Related Literature

SNS
PICO Info
in preparation
Languages

English

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